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      A Community-Based Intervention for Improving Medication Adherence for Elderly Patients with Hypertension in Korea

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          Abstract

          The chronic disease management program, a community-based intervention including patient education, recall and remind service, and reduction of out-of-pocket payment, was implemented in 2005 in Korea to improve patients’ adherence for antihypertensive medications. This study aimed to assess the effect of a community-based hypertension intervention intended to enhance patient adherence to prescribed medications. This study applied a non-equivalent control group design using the Korean National Health Insurance Big Data. Hongcheon County has been continuously implementing the intervention program since 2012. This study involved a cohort of patients with hypertension aged >65 and <85 years, among residents who lived in the study area for five years (between 2010 and 2014). The final number of subjects was 2685 in both the intervention and control region. The indirect indicators were analyzed as patients’ adherence and level of continuous treatment using the difference-in-difference regression. The proportion of hypertensive patients who continuously received insurance benefits for >240 days in 2014 was 81.0% in the intervention region and 79.7% in the control region. The number of dispensations per prescription and the dispensation days per hypertensive patient in the intervention region increased by approximately 10.88% and 2.2 days on average by month, respectively, compared to those in the control region. The intervention program encouraged elderly patients with hypertension to receive continuous care. Another research is needed to determine whether further improvement in the continuity of comprehensive care will prevent the progression of cardiovascular diseases.

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          Primary prevention of hypertension: clinical and public health advisory from The National High Blood Pressure Education Program.

          The National High Blood Pressure Education Program Coordinating Committee published its first statement on the primary prevention of hypertension in 1993. This article updates the 1993 report, using new and further evidence from the scientific literature. Current recommendations for primary prevention of hypertension involve a population-based approach and an intensive targeted strategy focused on individuals at high risk for hypertension. These 2 strategies are complementary and emphasize 6 approaches with proven efficacy for prevention of hypertension: engage in moderate physical activity; maintain normal body weight; limit alcohol consumption; reduce sodium intake; maintain adequate intake of potassium; and consume a diet rich in fruits, vegetables, and low-fat dairy products and reduced in saturated and total fat. Applying these approaches to the general population as a component of public health and clinical practice can help prevent blood pressure from increasing and can help decrease elevated blood pressure levels for those with high normal blood pressure or hypertension.
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            Adherence and health care costs

            Medication nonadherence is an important public health consideration, affecting health outcomes and overall health care costs. This review considers the most recent developments in adherence research with a focus on the impact of medication adherence on health care costs in the US health system. We describe the magnitude of the nonadherence problem and related costs, with an extensive discussion of the mechanisms underlying the impact of nonadherence on costs. Specifically, we summarize the impact of nonadherence on health care costs in several chronic diseases, such as diabetes and asthma. A brief analysis of existing research study designs, along with suggestions for future research focus, is provided. Finally, given the ongoing changes in the US health care system, we also address some of the most relevant and current trends in health care, including pharmacist-led medication therapy management and electronic (e)-prescribing.
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              Patient medication adherence: measures in daily practice.

              Adherence to therapies is a primary determinant of treatment success. Failure to adherence is a serious problem which not only affects the patient but also the health care system. Medication non adherence in patients leads to substantial worsening of disease, death and increased health care costs. A variety of factors are likely to affect adherence. Barriers to adherence could be addressed as patient, provider and health system factors, with interactions among them. Identifying specific barriers for each patient and adopting suitable techniques to overcome them will be necessary to improve medication adherence. Health care professionals such as physicians, pharmacists and nurses have significant role in their daily practice to improve patient medication adherence.
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                Author and article information

                Journal
                Int J Environ Res Public Health
                Int J Environ Res Public Health
                ijerph
                International Journal of Environmental Research and Public Health
                MDPI
                1661-7827
                1660-4601
                28 February 2019
                March 2019
                : 16
                : 5
                : 721
                Affiliations
                [1 ]Research Institute for Healthcare Policy, Korean Medical Association, Seoul 04373, Korea; sonkangju@ 123456hanmail.net
                [2 ]Hongcheon County Hypertension and Diabetes Registration and Education Center, Kangwon Province, Hongcheon 25135, Korea; hc_health@ 123456naver.com
                [3 ]Hongcheon County Health Center, Kangwon Province, Hongcheon 25135, Korea; pbh0118@ 123456korea.kr
                [4 ]Hoengseong County Health Center, Kangwon Province, Hoengseong 25220, Korea; Khja1231@ 123456korea.kr
                [5 ]Department of Preventive Medicine, Yonsei University Wonju College of Medicine, Wonju 26426, Korea
                [6 ]Institute for Poverty Alleviation and International Development, Yonsei University, Wonju 26493, Korea
                Author notes
                [* ]Correspondence: kimcb@ 123456yonsei.ac.kr ; Tel.: +82-(0)33-741-0344; Fax: +82-(0)33-747-0409
                Author information
                https://orcid.org/0000-0003-3272-7397
                https://orcid.org/0000-0003-1704-0650
                https://orcid.org/0000-0003-2798-4073
                https://orcid.org/0000-0002-3373-7127
                https://orcid.org/0000-0002-1979-6833
                Article
                ijerph-16-00721
                10.3390/ijerph16050721
                6427311
                30823383
                e00c00a1-7034-4a1b-ab8c-137b7d80077c
                © 2019 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                : 16 December 2018
                : 21 February 2019
                Categories
                Article

                Public health
                hypertension,medication adherence,community-based intervention,difference-in-difference regression

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