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Sugammadex for the reversal of muscle relaxation in general anaesthesia: a systematic review and economic assessment.
D Chambers
1 ,
M Paulden ,
F Paton ,
M Heirs ,
S Duffy ,
D Craig ,
J Hunter ,
J Wilson ,
M Sculpher ,
N Woolacott
Jul 2010
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Abstract
Sugammadex (Bridion) is a newly developed agent for the reversal of neuromuscular blockade (NMB) induced by rocuronium or vecuronium. Sugammadex can reverse profound blockade and can be given for immediate reversal and its use would avoid the potentially serious adverse effects of the currently used agent, succinylcholine. Also, sugammadex can reverse NMB more quickly and predictably than existing agents.