Magnitude-dependent proliferation and contractility modulation of human bladder smooth muscle cells under physiological stretch.

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Abstract

The purpose of this study was to describe and test a kind of stretch pattern which is based on modified BOSE BioDynamic system to produce optimum physiological stretch during bladder cycle. Moreover, we aimed to emphasize the effects of physiological stretch's amplitude upon proliferation and contractility of human bladder smooth muscle cells (HBSMCs).

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Author and article information

Journal

Journal ID (iso-abbrev): World J Urol

Title: World journal of urology

Publisher: Springer Nature America, Inc

ISSN (Electronic): 1433-8726

ISSN (Print): 0724-4983

Publication date (Electronic): Nov 2015

Volume: 33

Issue: 11

Affiliations

[1 ] Department of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.

[2 ] Department of Urologic Sciences, The University of British Columbia, Vancouver, BC, Canada.

[3 ] Immunity and Infection Research Centre, Vancouver Coastal Health Research Institute, Vancouver, BC, Canada.

[4 ] Department of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China. wangkj@scu.edu.cn.

Article

Publisher Item ID: 10.1007/s00345-015-1509-4

DOI: 10.1007/s00345-015-1509-4

PubMed ID: 25678345

SO-VID: e0667ca0-4271-4538-b946-1f091c5ec00d

History

Keywords: Contractility,Proliferation,Stretch,Bladder smooth muscle cell

Data availability:

Keywords: Contractility, Proliferation, Stretch, Bladder smooth muscle cell

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