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Magnitude-dependent proliferation and contractility modulation of human bladder smooth muscle cells under physiological stretch.

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      Abstract

      The purpose of this study was to describe and test a kind of stretch pattern which is based on modified BOSE BioDynamic system to produce optimum physiological stretch during bladder cycle. Moreover, we aimed to emphasize the effects of physiological stretch's amplitude upon proliferation and contractility of human bladder smooth muscle cells (HBSMCs).

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      Affiliations
      [1 ] Department of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
      [2 ] Department of Urologic Sciences, The University of British Columbia, Vancouver, BC, Canada.
      [3 ] Immunity and Infection Research Centre, Vancouver Coastal Health Research Institute, Vancouver, BC, Canada.
      [4 ] Department of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China. wangkj@scu.edu.cn.
      Journal
      World J Urol
      World journal of urology
      Springer Nature America, Inc
      1433-8726
      0724-4983
      Nov 2015
      : 33
      : 11
      25678345
      10.1007/s00345-015-1509-4
      10.1007/s00345-015-1509-4

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