Total mutation burden (TMB) in lung cancer (LC) and relationship with response to PD-1/PD-L1 targeted therapies.

Ou, Sai-Hong Ignatius; Raez, Luis E; Kalemkerian, Gregory Peter; Bauer, Todd Michael; Johnson, Melissa Lynne; Schrock, Alexa Betzig; Spigel, David R; Gowen, Kyle A; He, Jie; Sun, James; Miller, Vincent A.; Ali, Siraj Mahamed; Frampton, Garrett Michael; Fabrizio, David; Ross, Jeffrey S.; Stephens, Philip J.

doi:10.1200/JCO.2016.34.15_suppl.9017

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Total mutation burden (TMB) in lung cancer (LC) and relationship with response to PD-1/PD-L1 targeted therapies.

Author(s): David R. Spigel ¹ , Alexa Betzig Schrock ² , David Fabrizio ³ , Garrett Michael Frampton ² , James Sun ² , Jie He ² , Kyle Gowen ² , Melissa Lynne Johnson ¹ , Todd Michael Bauer ⁴ , Gregory Peter Kalemkerian ⁵ , Luis E. Raez ⁶ , Sai-Hong Ignatius Ou ⁷ , Jeffrey S. Ross ⁸ , Philip J. Stephens ² , Vincent A. Miller ² , Siraj Mahamed Ali ²

Publication date Created: May 20 2016

Publication date (Print): May 20 2016

Journal: Journal of Clinical Oncology

Publisher: American Society of Clinical Oncology (ASCO)

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Title: Journal of Clinical Oncology

Abbreviated Title: JCO

Publisher: American Society of Clinical Oncology (ASCO)

ISSN (Print): 0732-183X

ISSN (Electronic): 1527-7755

Publication date Created: May 20 2016

Publication date (Print): May 20 2016

Volume: 34

Issue: 15_suppl

Page: 9017

Affiliations

[1 ]Sarah Cannon Research Institute, Nashville, TN;

[2 ]Foundation Medicine, Inc., Cambridge, MA;

[3 ]Foundation Medicine, Boston, MA;

[4 ]Sarah Cannon Research Institute, and Tennessee Oncology, PLLC., Nashville, TN;

[5 ]University of Michigan, Ann Arbor, MI;

[6 ]Memor Cancer Inst, Pembroke Pines, FL;

[7 ]Chao Family Comprehensive Cancer Center, University of California Irvine, Orange County, CA;

[8 ]Albany Medical College, Albany, NY;

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DOI: 10.1200/JCO.2016.34.15_suppl.9017

SO-VID: e0c69395-185e-4762-928f-6ac4796c0b83

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Total mutation burden (TMB) in lung cancer (LC) and relationship with response to PD-1/PD-L1 targeted therapies.

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