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      Correlates of suicide attempt history in bipolar disorder: a stress-diathesis perspective.

      Bipolar Disorders
      Adult, Aged, Aggression, psychology, Bipolar Disorder, drug therapy, epidemiology, Demography, Depressive Disorder, Major, Disease Susceptibility, Female, Hostility, Humans, Life Change Events, Male, Middle Aged, Questionnaires, Risk Factors, Severity of Illness Index, Stress, Psychological, Suicide, statistics & numerical data, Suicide, Attempted

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          Abstract

          Distinguishing clinical characteristics of bipolar patients who have made a suicide attempt may help to identify at-risk individuals. We sought to identify such factors and to consider them within a stress-diathesis model of suicidal behavior. Patients with bipolar disorder (N = 96) were compared with respect to the presence or absence at baseline evaluation of a history of suicide attempt. We used multiple logistic regression analysis to assess the unique associations of independent variables to history of a past suicide attempt. The regression analysis showed that a history of suicide attempt in bipolar disorder was associated with greater recent suicidal ideation, more psychiatric hospitalizations, lifetime aggressive traits and an earlier age at onset of a first mood episode. Aggressive traits and early treatment of mood disorders, especially major depressive episodes, are potential targets for suicide prevention in bipolar disorder.

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