- Record: found
- Abstract: found
- Article: not found
Pivotal role of mTOR signaling in hepatocellular carcinoma.
Augusto Villanueva
1 ,
Derek Y Chiang ,
Pippa Newell ,
Judit Peix ,
Swan Thung ,
Clara Alsinet ,
Victoria Tovar ,
Sasan Roayaie ,
Beatriz Minguez ,
Manel Sole ,
Carlo Battiston ,
Stijn Van Laarhoven ,
Maria I Fiel ,
Analisa Di Feo ,
Yujin Hoshida ,
Steven Yea ,
Sara Toffanin ,
Alex Ramos ,
John A Martignetti ,
Vincenzo Mazzaferro ,
Jordi Bruix ,
Samuel Waxman ,
Myron Schwartz ,
Matthew Meyerson ,
Scott L Friedman ,
Josep M Llovet
Dec 2008
Read this article at
There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
Abstract
The advent of targeted therapies in hepatocellular carcinoma (HCC) has underscored the importance of pathway characterization to identify novel molecular targets for treatment. We evaluated mTOR signaling in human HCC, as well as the antitumoral effect of a dual-level blockade of the mTOR pathway.