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      Correlations of water quality parameters with mutagenicity of chlorinated drinking water samples.

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          Abstract

          Adverse health effects that may result from chronic exposure to mixtures of disinfection by-products (DBPs) present in drinking waters may be linked to both the types and concentrations of DBPs present. Depending on the characteristics of the source water and treatment processes used, both types and concentrations of DBPs found in drinking waters vary substantially. The composition of a drinking-water mixture also may change during distribution. This study evaluated the relationships between mutagenicity, using the Ames assay, and water quality parameters. The study included information on treatment, mutagenicity data, and water quality data for source waters, finished waters, and distribution samples collected from five full-scale drinking water treatment plants, which used chlorine exclusively for disinfection. Four of the plants used surface water sources and the fifth plant used groundwater. Correlations between mutagenicity and water quality parameters are presented. The highest correlation was observed between mutagenicity and the total organic halide concentrations in the treated samples.

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          Author and article information

          Journal
          J. Toxicol. Environ. Health Part A
          Journal of toxicology and environmental health. Part A
          Informa UK Limited
          1528-7394
          0098-4108
          2009
          : 72
          : 7
          Affiliations
          [1 ] U.S. Environmental Protection Agency, Cincinnati, Ohio 45268, USA. schenck.kathleen@epa.gov
          Article
          909289079
          10.1080/15287390802608940
          19267307
          e143e8ba-d86c-4e4e-a8b1-de25c07d3f09
          History

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