The main objective of this study was to find out how well three non-contact tonometers (Pulsair, Xpert-NCT and CT-20) compare with the Goldmann tonometer (GT). Sensitivity, specificity, positive and negative predictive values were all evaluated for an intraocular pressure (IOP) ≧21 mm Hg. We also calculated the mean IOP, the correlation and the dispersion of the results. The difficulty in using the instruments, the patient’s attitude and subjective comfort of IOP measuring were also evaluated. We describe the advantages and shortcomings of non-contact tonometers as screening tools to detect elevated IOP in the general population.