3
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Further studies on the clinical efficacy of Solanum xanthocarpum and Solanum trilobatum in bronchial asthma.

      1 , , ,
      Phytotherapy research : PTR
      Wiley

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          The clinical efficacy of two herbs S. xanthocarpum and S. trilobatum in a dose of 300 mg tds for 3 days was investigated in mild to moderate bronchial asthma. Their effect was compared with standard bronchodilator drugs, salbutamol (4 mg) and deriphylline (200 mg). The respiratory function was assessed by measuring the peak expiratory flow rate (PEFR) using a mini peak flow meter. In addition, improvement in lung function was assessed by physical examination (rhonchi and crepitation) and other symptoms such as cough, breathlessness and sputum. S. xanthocarpum and S. trilobatum produced a progressive improvement in the ventilatory function of asthmatic individuals over 3 days. The scores for rhonchi, cough, breathlessness and sputum were decreased by these drug treatments. The improvement in PEFR and the reduction in other symptom scores clearly indicate a bronchodilator effect, a decrease of oedema and secretions in the airway lumen. The response to these herbs can be considered to be equivalent to that of deriphylline but less than salbutamol. No untoward effects were reported during the study. The present study further confirms the traditional use of these herbs in bronchial asthma.

          Related collections

          Author and article information

          Journal
          Phytother Res
          Phytotherapy research : PTR
          Wiley
          0951-418X
          0951-418X
          Oct 2004
          : 18
          : 10
          Affiliations
          [1 ] Institute of Internal Medicine, Madras Medical College, Government General Hospital, Chennai 600 033, India.
          Article
          10.1002/ptr.1555
          15551394
          e1912c41-c44d-44ab-a70a-443e23c4a5e4
          History

          Comments

          Comment on this article