Arturo Medrano-Soto: Role: ConceptualizationRole: Formal analysisRole: MethodologyRole: SoftwareRole: ValidationRole:
VisualizationRole: Writing – original draftRole: Writing – review & editing
Gabriel Moreno-Hagelsieb: Role: ConceptualizationRole: Formal analysisRole: MethodologyRole: SoftwareRole: ValidationRole:
VisualizationRole: Writing – review & editing
Daniel McLaughlin: Role: Formal analysisRole: InvestigationRole: MethodologyRole: VisualizationRole:
Writing – original draft
Zachary S. Ye: Role: Formal analysisRole: InvestigationRole: MethodologyRole: VisualizationRole:
Writing – original draft
Kevin J. Hendargo: Role: MethodologyRole: Software
Milton H. Saier Jr.:
ORCID: http://orcid.org/0000-0001-5530-0017
Role: ConceptualizationRole: Data curationRole: Funding acquisitionRole: ResourcesRole:
SupervisionRole: ValidationRole: VisualizationRole: Writing – review & editing
Olaf Strauß: Role: Editor
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
26
March
2018
Publication date Collection: 2018
Volume: 13
Issue: 3
Electronic Location Identifier: e0192851
Affiliations
[1
]
Department of Molecular Biology, University of California at San Diego, La Jolla,
California, United States of America
[2
]
Department of Biology, Wilfrid Laurier University, Waterloo, Ontario, Canada
Eye Hospital, Charité, GERMANY
Author notes
Competing Interests: The authors have declared that no competing interests exist.
Author information
Article
Publisher ID:
PONE-D-17-30095
DOI: 10.1371/journal.pone.0192851
PMC ID: 5868767
PubMed ID: 29579047
SO-VID: e1945e39-d5de-4dbd-ab24-f6c14e220223
Copyright © © 2018 Medrano-Soto et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by: funder-id http://dx.doi.org/10.13039/100000002, National Institutes of Health;
Award ID: GM077402
Award Recipient
: Milton H. Saier Jr
Funded by: funder-id http://dx.doi.org/10.13039/100000001, National Science Foundation;
Award ID: IOS-1444435
Award Recipient
: Milton H. Saier Jr
This work was supported by NIH grant GM077402 and NSF grant IOS-1444435. The funders
had no role in study design, data collection and analysis, decision to publish, or
preparation of the manuscript.
Subject:
Research Article
Subject:
Research and Analysis Methods
Subject:
Database and Informatics Methods
Subject:
Bioinformatics
Subject:
Sequence Analysis
Subject:
Sequence Alignment
Subject:
Research and Analysis Methods
Subject:
Computational Techniques
Subject:
Split-Decomposition Method
Subject:
Multiple Alignment Calculation
Subject:
Research and Analysis Methods
Subject:
Database and Informatics Methods
Subject:
Bioinformatics
Subject:
Sequence Analysis
Subject:
Sequence Motif Analysis
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
Protein Domains
Subject:
Biology and Life Sciences
Subject:
Evolutionary Biology
Subject:
Evolutionary Systematics
Subject:
Phylogenetics
Subject:
Phylogenetic Analysis
Subject:
Biology and Life Sciences
Subject:
Taxonomy
Subject:
Evolutionary Systematics
Subject:
Phylogenetics
Subject:
Phylogenetic Analysis
Subject:
Computer and Information Sciences
Subject:
Data Management
Subject:
Taxonomy
Subject:
Evolutionary Systematics
Subject:
Phylogenetics
Subject:
Phylogenetic Analysis
Subject:
Biology and Life Sciences
Subject:
Molecular Biology
Subject:
Macromolecular Structure Analysis
Subject:
Protein Structure
Subject:
Protein Structure Comparison
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
Protein Structure
Subject:
Protein Structure Comparison
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Structures and Organelles
Subject:
Cell Membranes
Subject:
Membrane Proteins
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Physical Chemistry
Subject:
Ions
Subject:
Cations
