Mortality and extraintestinal cancers in patients with primary sclerosing cholangitis and inflammatory bowel disease.

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Abstract

Primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD) frequently co-occur. PSC is associated with increased risk for colorectal cancer (CRC). However, whether PSC is associated with increased risk of extraintestinal cancers or affects mortality in an IBD cohort has not been examined previously.

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Journal

Journal ID (iso-abbrev): J Crohns Colitis

Title: Journal of Crohn's & colitis

Publisher: Elsevier BV

ISSN (Electronic): 1876-4479

ISSN (Print): 1873-9946

Publication date (Electronic): Sep 2014

Volume: 8

Issue: 9

Affiliations

[1 ] Division of Gastroenterology, Massachusetts General Hospital, Boston, MA, United States; Harvard Medical School, Boston, MA, United States. Electronic address: aananthakrishnan@partners.org.

[2 ] Research IS and Computing, Partners HealthCare, Charlestown, MA, United States.

[3 ] Department of Biostatistics, Harvard School of Public Health, Boston, MA, United States.

[4 ] Massachusetts Institute of Technology, Cambridge, MA, United States.

[5 ] Harvard Medical School, Boston, MA, United States; Center for Systems Biology, Massachusetts General Hospital, Boston, MA, United States.

[6 ] i2b2 National Center for Biomedical Computing, Brigham and Women's Hospital, Boston, MA, United States.

[7 ] Harvard Medical School, Boston, MA, United States; Division of Rheumatology, Allergy and Immunology, Brigham and Women's Hospital, Boston, MA, United States.

[8 ] Harvard Medical School, Boston, MA, United States; Research IS and Computing, Partners HealthCare, Charlestown, MA, United States; Department of Neurology, Massachusetts General Hospital, Boston, MA, United States.

[9 ] Harvard Medical School, Boston, MA, United States; Children's Hospital Boston, Boston, MA, United States; i2b2 National Center for Biomedical Computing, Brigham and Women's Hospital, Boston, MA, United States.

Article

Publisher Item ID: S1873-9946(14)00038-5 Mid ID: NIHMS562609

DOI: 10.1016/j.crohns.2014.01.019

PMC ID: 4136996

PubMed ID: 24559536

SO-VID: e22c3079-5438-46d8-862f-d7bef234f784

History

Keywords: Cancer;,Colorectal cancer,Crohn's disease;,Sclerosing cholangitis;,Ulcerative colitis;

Data availability:

Keywords: Cancer;, Colorectal cancer, Crohn's disease;, Sclerosing cholangitis;, Ulcerative colitis;

Mortality and extraintestinal cancers in patients with primary sclerosing cholangitis and inflammatory bowel disease.

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Karger: Gastroenterology

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