Bringing nano-enabled developments to the market still faces challenges along up-scaling processes and safety evaluation  and needs to be addressed in a structured way . In addition, a major aim is to assess the safety profiles of engineered nanomaterials (ENMs) at low, nonlethal dosages and extended repetitive exposures, which could help to understand long-term consequences of ENMs’ interactions with biological environments and further expedite their translation into products and applications. To enable this translation, data plays a prominent role. And here is where NanoCommons, the e-infrastructure project, as one of the three EU-H2020 data relevant projects (together with NanoSolveIT and NanoinformaTIX) can help nanosafety researchers from industry, academia and regulatory bodies to access the state-of-the-art data management expertise. Thus, users/collaborators can take advantage of the NanoCommons services, facilities and knowledge to advance their work, solve problems and take their research to the next level. Within this contribution, it is presented, how NanoCommons, by means of its transnational actions (TAs), brings benefits to its users/collaborators: (i) EU funded access to expertise in data management and nanoinformatics tools; (ii) Facilitate open access data to help reduce duplication of tests, regulation, animal-testing, bureaucracy…; (iii) Assistance with capture and databasing of data to comply with EU open data initiatives and achieve FAIR data principles; (iv) model development; and many more.