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      Sarcosine or D-serine add-on treatment for acute exacerbation of schizophrenia: a randomized, double-blind, placebo-controlled study.

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      Publication date:
      Journal: Archives of general psychiatry
      Publisher: American Medical Association (AMA)

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          Abstract

          Agents that enhance N-methyl-D-aspartate (NMDA) function through the glycine modulatory site (D-serine, glycine, or D-cycloserine) or through glycine transporter 1 (sarcosine) improve the symptoms of patients with stable chronic schizophrenia.

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          PubMed ID:: 16275807
          DOI:: 10.1001/archpsyc.62.11.1196

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