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      Enzymatically and Electrocardiographically Estimated Infarct Size in Relation to Pain in Acute Myocardial Infarction

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          In 563 patients with acute myocardial infarction and no previous myocardial infarction, the estimated infarct size was related to the estimated duration of pain and the amount of analgesics given. The size of infarction estimated from analyses of heat-stable lactate dehydrogenase (EC at 12-hour intervals for 48–108 h and from Q- and R-wave changes in the ECG correlated positively, although weakly with duration of the pain and the amount of analgesics given. These data support the hypothesis that larger infarcts, as a group, evolve over a longer time period than smaller infarcts and that the duration of pain in many patients might be an indicator of the infarct size. In the individual patient, however, one cannot predict the size of the infarction from the severity of pain.

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          Author and article information

          S. Karger AG
          11 November 2008
          : 71
          : 5
          : 239-246
          Departments of aMedicine I and bClinical Chemistry, University of Gothenburg, Sahlgren’s Hospital, Gothenburg; cDepartment of Medicine, Östra Sjukhuset, Gothenburg, Sweden
          173672 Cardiology 1984;71:239–246
          © 1984 S. Karger AG, Basel

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          Page count
          Pages: 8
          Original Paper

          General medicine, Neurology, Cardiovascular Medicine, Internal medicine, Nephrology

          Pain, Enzymes, ECG, Infarct size


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