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      Intersonographer Reproducibility and Intermethod Variability of Ultrasound Measurements of Carotid Artery Stenosis: The Tromsø Study

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          Abstract

          Background and Purpose: Knowledge of the reproducibility of a diagnostic method is important in order to evaluate its usefulness. Few studies have examined interobserver and intermethod agreement on ultrasound measurements of carotid stenosis. Methods: Intersonographer agreement on ultrasound measurements of carotid plaque morphology and the estimated degree of stenosis by three ultrasound methods were assessed in a random sample of 51 participants with stenotic carotid arteries selected from a population health survey. The degree of stenosis was assessed by measurements of velocity, lumen diameter reduction and cross-sectional lumen area. Intermethod agreement on the degree of carotid stenosis was also assessed. Results: Agreement on plaque echogenicity and heterogeneity was moderate (κ = 0.56 and κ = 0.60, respectively). The mean degree of stenosis and median absolute difference between observers of the estimated degree of stenosis by the velocity method were 46.3 and 10.8%, respectively. The corresponding values were 51.0 and 5.8% for the diameter method, and 57.1 and 7.2%, for the cross-sectional lumen method. The limits of agreement for intersonographer reproducibility varied between ±19.7 and 26.5%. For all methods, reproducibility increased with increasing degree of stenosis. Differences between the methods were large in low-grade stenosis but were acceptable in high-grade stenosis. Conclusions: Considerable differences in ultrasound measurement of stenosis, which could lead to different clinical conclusions, were regularly encountered no matter what ultrasound method was used.

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          Reproducibility in Ultrasonic Characterization of Carotid Plaques

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            Author and article information

            Journal
            CED
            Cerebrovasc Dis
            10.1159/issn.1015-9770
            Cerebrovascular Diseases
            S. Karger AG
            1015-9770
            1421-9786
            2000
            June 2000
            18 April 2000
            : 10
            : 3
            : 207-213
            Affiliations
            Institute of Community Medicine and Institute of Clinical Medicine, University of Tromsø, Norway
            Article
            16058 Cerebrovasc Dis 2000;10:207–213
            10.1159/000016058
            10773647
            © 2000 S. Karger AG, Basel

            Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

            Page count
            Figures: 3, Tables: 3, References: 23, Pages: 7
            Categories
            Original Paper

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