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      Synthèse et affinité de fixation aux récepteurs d’hormones stéroïdes humains de 3-phénoxy-4-hydroxycoumarines et de 3-phénoxy-4-phénylcoumarines

      , ,
      Annales Pharmaceutiques Françaises
      Elsevier BV

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          Abstract

          <p class="first" id="d3853038e85">The synthesis and the study of the binding affinity to human receptors of glucocorticoids, mineralcorticoids, androgens, estrogens and progesterone of 3-phenoxy-4-hydroxycoumarins and 3-phenoxy-4-phenylcoumarins were performed. It shows the absence of any binding affinity of all these derivatives to glucocorticoid and mineralcorticoid receptors and a non-selective binding affinity to androgen, oestrogen and progesterone receptors with 3-phenoxy-4-phényl-coumarins. </p>

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          Author and article information

          Journal
          Annales Pharmaceutiques Françaises
          Annales Pharmaceutiques Françaises
          Elsevier BV
          00034509
          November 2017
          November 2017
          : 75
          : 6
          : 455-462
          Article
          10.1016/j.pharma.2017.04.007
          28619467
          e38feff6-dbfb-4a1f-88a0-f8622e39462d
          © 2017

          https://www.elsevier.com/tdm/userlicense/1.0/

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