Hepatotoxicity associated with cocaine abuse.

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Abstract

The mechanisms evaluated in animals as being responsible for cocaine associated hepatotoxicity are presented. The importance of the P-450 enzyme system in cocaine associated hepatotoxicity is emphasized. Moreover, the putative critical role of free radicals in such injury is discussed. Finally, the growing literature on clinical cases of cocaine hepatotoxicity is reviewed.

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Journal

Journal ID (iso-abbrev): Recent Dev Alcohol

Title: Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism

Publisher: Springer Science and Business Media LLC

ISSN: 0738-422X

ISSN (Print): 0738-422X

Publication date (Electronic): 1992

Volume: 10

Affiliations

[1 ] Department of Surgery, University of Pittsburgh School of Medicine, Pennsylvania 15213.

Article

DOI: 10.1007/978-1-4899-1648-8_16

PubMed ID: 1589605

SO-VID: e4128176-779c-4dd8-9d5e-5a181f9a6581

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