6
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Non-invasive positive pressure ventilation for the treatment of severe stable chronic obstructive pulmonary disease: a prospective, multicentre, randomised, controlled clinical trial.

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Evidence is weak for the ability of long-term non-invasive positive pressure ventilation (NPPV) to improve survival in patients with stable hypercapnic chronic obstructive pulmonary disease (COPD). Previous prospective studies did not target a reduction in hypercapnia when adjusting ventilator settings. This study investigated the effect of long-term NPPV, targeted to markedly reduce hypercapnia, on survival in patients with advanced, stable hypercapnic COPD.

          Related collections

          Author and article information

          Journal
          Lancet Respir Med
          The Lancet. Respiratory medicine
          2213-2619
          2213-2600
          Sep 2014
          : 2
          : 9
          Affiliations
          [1 ] From the Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany. Electronic address: koehnlein.thomas@mh-hannover.de.
          [2 ] Centre for Respiratory Medicine, Hospital Köln-Merheim, University of Witten/Herdecke, Cologne, Germany.
          [3 ] Department of Pneumology I, Fachkrankenhaus Kloster Grafschaft, Schmallenberg, Germany.
          [4 ] Department of Medical Biometry and Epidemiology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
          [5 ] Centre of Pneumology and Thoracic Surgery, Asklepios Hospital Gauting, Department of Intensive Care Medicine and Long-term Ventilation, Gauting, Germany.
          [6 ] Department of Respiratory and Critical Care Medicine, and Ludwig Boltzmann Institute of COPD and Respiratory Epidemiology, Otto Wagner Hospital, Vienna, Austria.
          [7 ] Department of Respiratory Medicine, Evangelisches Klinikum Niederrhein, Oberhausen, Germany.
          [8 ] Department of Specialist, Diagnostic, and Experimental Medicine, School of Medicine, Università di Bologna, Bologna, Italy.
          [9 ] Department of Respiratory Medicine, Klinikum Oststadt-Heidehaus, Hannover, Germany.
          [10 ] LungenClinic Grosshansdorf, Center for Pneumology and Thoracic Surgery, Grosshansdorf, Germany.
          [11 ] Department of Pneumology, Respiratory Care, and Sleep Medicine, Evangelisches Krankenhaus Göttingen-Weende, Bovenden-Lenglern, Germany.
          [12 ] Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany; Member of the German Centre for Lung Research.
          Article
          S2213-2600(14)70153-5
          10.1016/S2213-2600(14)70153-5
          25066329
          Copyright © 2014 Elsevier Ltd. All rights reserved.

          Comments

          Comment on this article