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      Technologies for Opioid Use Disorder Management: Mobile App Search and Scoping Review

      research-article
      , BSc, MSc, PhD 1 , , BEng, MEng, PhD 1 , , BA, BCS, MASc, SM, PhD 1 , 2 ,
      (Reviewer), (Reviewer), (Reviewer)
      JMIR mHealth and uHealth
      JMIR Publications
      mHealth, apps, wearable sensors, substance abuse disorder, mobile phone

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          Abstract

          Background

          Advances in technology engender the investigation of technological solutions to opioid use disorder (OUD). However, in comparison to chronic disease management, the application of mobile health (mHealth) to OUD has been limited.

          Objective

          The overarching aim of our research was to design OUD management technologies that utilize wearable sensors to provide continuous monitoring capabilities. The objectives of this study were to (1) document the currently available opioid-related mHealth apps, (2) review past and existing technology solutions that address OUD, and (3) discuss opportunities for technological withdrawal management solutions.

          Methods

          We used a two-phase parallel search approach: (1) an app search to determine the availability of opioid-related mHealth apps and (2) a scoping review of relevant literature to identify relevant technologies and mHealth apps used to address OUD.

          Results

          The app search revealed a steady rise in app development, with most apps being clinician-facing. Most of the apps were designed to aid in opioid dose conversion. Despite the availability of these apps, the scoping review found no study that investigated the efficacy of mHealth apps to address OUD.

          Conclusions

          Our findings highlight a general gap in technological solutions of OUD management and the potential for mHealth apps and wearable sensors to address OUD.

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          Most cited references56

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          Societal costs of prescription opioid abuse, dependence, and misuse in the United States.

          The objective of this study was to estimate the societal costs of prescription opioid abuse, dependence, and misuse in the United States. Costs were grouped into three categories: health care, workplace, and criminal justice. Costs were estimated by 1) quantity method, which multiplies the number of opioid abuse patients by cost per opioid abuse patient; and 2) apportionment method, which begins with overall costs of drug abuse per component and apportions the share associated with prescription opioid abuse based on relative prevalence of prescription opioid to overall drug abuse. Excess health care costs per patient were based on claims data analysis of privately insured and Medicaid beneficiaries. Other data/information were derived from publicly available survey and other secondary sources. Total US societal costs of prescription opioid abuse were estimated at $55.7 billion in 2007 (USD in 2009). Workplace costs accounted for $25.6 billion (46%), health care costs accounted for $25.0 billion (45%), and criminal justice costs accounted for $5.1 billion (9%). Workplace costs were driven by lost earnings from premature death ($11.2 billion) and reduced compensation/lost employment ($7.9 billion). Health care costs consisted primarily of excess medical and prescription costs ($23.7 billion). Criminal justice costs were largely comprised of correctional facility ($2.3 billion) and police costs ($1.5 billion).   The costs of prescription opioid abuse represent a substantial and growing economic burden for the society. The increasing prevalence of abuse suggests an even greater societal burden in the future. Wiley Periodicals, Inc.
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            An autonomic flexibility-neurovisceral integration model of anxiety and cardiac vagal tone.

            Research on heart rate variability (HRV), cardiac vagal tone, and their relationship to anxiety is reviewed in the context of the autonomic flexibility and neurovisceral integration models of adaptive functioning. These perspectives address the qualities of response flexibility and inhibition across multiple levels, incorporating central and autonomic nervous system mechanisms of environmental engagement, as well as principles derived from non-linear dynamics. These models predict reduced HRV and vagal tone in anxiety, and the literature has generally supported this prediction, with exceptions as are noted. State, trait, and clinical expressions of anxiety are considered, along with the clinical, methodological, and theoretical implications of this research. A portrayal of anxiety as a restricted response range across biological and behavioral realms of functioning is drawn from the literature on anxiety and HRV.
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              Treatment of Opioid-Use Disorders.

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                Author and article information

                Contributors
                Journal
                JMIR Mhealth Uhealth
                JMIR Mhealth Uhealth
                JMU
                JMIR mHealth and uHealth
                JMIR Publications (Toronto, Canada )
                2291-5222
                June 2020
                5 June 2020
                : 8
                : 6
                : e15752
                Affiliations
                [1 ] Department of Industrial and Systems Engineering Texas A&M University College Station, TX United States
                [2 ] Center for Outcomes Research Houston Methodist Hospital Houston, TX United States
                Author notes
                Corresponding Author: Farzan Sasangohar sasangohar@ 123456tamu.edu
                Author information
                https://orcid.org/0000-0001-7172-0716
                https://orcid.org/0000-0002-8254-8365
                https://orcid.org/0000-0001-9962-5470
                Article
                v8i6e15752
                10.2196/15752
                7305558
                32501273
                e480f030-fd7a-4fec-84b2-1ce93e4b2cdc
                ©Joseph Nuamah, Ranjana Mehta, Farzan Sasangohar. Originally published in JMIR mHealth and uHealth (http://mhealth.jmir.org), 05.06.2020.

                This is an open-access article distributed under the terms of the Creative Commons Attribution License ( https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR mHealth and uHealth, is properly cited. The complete bibliographic information, a link to the original publication on http://mhealth.jmir.org/, as well as this copyright and license information must be included.

                History
                : 2 August 2019
                : 15 October 2019
                : 19 January 2020
                : 1 March 2020
                Categories
                Original Paper
                Original Paper

                mhealth,apps,wearable sensors,substance abuse disorder,mobile phone

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