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      Measurement of prostate-specific antigen in serum as a screening test for prostate cancer.

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          Abstract

          Prostate-specific antigen (PSA) is secreted exclusively by prostatic epithelial cells, and its serum concentration is increased in men with prostatic disease, including cancer. We evaluated its usefulness in the detection and staging of prostate cancer.

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          Author and article information

          Journal
          N Engl J Med
          The New England journal of medicine
          Massachusetts Medical Society
          0028-4793
          0028-4793
          Apr 25 1991
          : 324
          : 17
          Affiliations
          [1 ] Department of Surgery, Washington University School of Medicine, St. Louis, MO.
          Article
          10.1056/NEJM199104253241702
          1707140
          e4948fe7-ae56-4ca2-a0d9-f0294fa68e24
          History

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