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      First isolation of sesquiterpenes and flavonoids from Zingiber spectabile and identification of zerumbone as the major cell growth inhibitory component.

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          Abstract

          Nine sesquiterpenes and eight flavonoids were isolated from Zingiber spectabile for the first time. Structures were determined by spectroscopic methods. The major compound zerumbone (1) was found to be the most active (IC(50) 13 microg mL(-1)) in cell growth inhibitory assay against colon carcinoma SW480 cells.

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          Author and article information

          Journal
          Nat. Prod. Res.
          Natural product research
          1478-6419
          1478-6419
          Dec 2007
          : 21
          : 14
          Affiliations
          [1 ] Graduate School of Pharmaceutical Sciences, Chiba University, Inage-ku, Chiba 263-8522, Japan.
          Article
          788425753
          10.1080/14786410701371421
          18075886
          e4acb234-6770-4b13-bfb7-0d20770f49a0
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