Blog
About

0
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: not found
      • Article: not found

      Does the microbiota regulate immune responses outside the gut?

      ,

      Trends in Microbiology

      Elsevier BV

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Perturbations in the gastrointestinal (GI) microbiota composition that occur as a result of antibiotics and diet in "westernized" countries are strongly associated with allergies and asthma ("hygiene hypothesis"). The microbiota ("microflora") plays a crucial role in the development of mucosal tolerance, including the airways. Significant attention has been focused on the role of the microbiota in GI development, immune adaptation and initiation of GI inflammatory diseases. This review covers the post-developmental functions that the microbiota plays in regulating immunological tolerance to allergen exposure outside the GI tract and proposes the question: is the microbiota a major regulator of the immune system?

          Related collections

          Author and article information

          Journal
          Trends in Microbiology
          Trends in Microbiology
          Elsevier BV
          0966842X
          December 2004
          December 2004
          : 12
          : 12
          : 562-568
          Article
          10.1016/j.tim.2004.10.008
          15539116
          © 2004

          http://www.elsevier.com/tdm/userlicense/1.0/

          Comments

          Comment on this article