9
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Automated estimated GFR reporting: A new tool to promote safer prescribing in patients with chronic kidney disease?

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          A number of drugs rely on the kidney for excretion and thus require their dose to be modified in any patients where there is renal impairment. Others are nephrotoxic and should be avoided completely in patients with renal disease. Traditionally clinicians have had to rely on serum creatinine to assess renal function but this may not accurately reflect the kidney function of an individual since its level also depends on muscle mass. In particular elderly females may have significant impairment of renal function despite a normal or near normal serum creatinine. The advent of automated reporting of estimated glomerular filtration rate (eGFR) provides the clinician with simple, easily understood and readily available measurement which more accurately reflects a patient’s renal function. In particular eGFR allows the clinician to readily identify and stratify patients with chronic kidney disease (CKD) and can allow a more rational and safer approach to prescribing in this group of high risk patients. This commentary suggests that national prescribing formularies should use eGFR to provide consistent advice about the appropriate dose adjustment and avoidance of potentially toxic drugs at various stages of CKD. Such an approach may prove invaluable in improving prescribing in CKD and avoiding drug toxicity in this group of patients.

          Related collections

          Most cited references 3

          • Record: found
          • Abstract: not found
          • Article: not found

          Chronic kidney disease in adults: UK guidelines for identification, management and referral [online]

          (2021)
            Bookmark
            • Record: found
            • Abstract: not found
            • Article: not found

            A simplified equation to predict glomerular filtration rate from serum creatinine

             AS Levey,  T Greene,  JW Kusek (2000)
              Bookmark
              • Record: found
              • Abstract: not found
              • Article: not found

              A simplified equation to predict glomerular filtration rate from serum creatinine

               JW Kusek,  AS Levey,  T Greene (2000)
                Bookmark

                Author and article information

                Journal
                Ther Clin Risk Manag
                Therapeutics and Clinical Risk Management
                Therapeutics and Clinical Risk Management
                Dove Medical Press
                1176-6336
                1178-203X
                October 2007
                October 2007
                : 3
                : 5
                : 969-972
                Affiliations
                [1 ]University Hospitals of Leicester NHS Trust
                [2 ]East Midlands Renal Network
                Author notes
                Correspondence: KPG Harris John Walls Renal Unit, Leicester General Hospital, Leicester LE54PW, UK Tel +44 116 258 4195 Fax +44 116 258 4764 Email krgh1@ 123456le.ac.uk
                Article
                2376075
                18473020
                © 2007 Dove Medical Press Limited. All rights reserved
                Categories
                Commentary

                Medicine

                chronic kidney disease, prescribing, egfr

                Comments

                Comment on this article