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      Angiogenesis in life, disease and medicine.

      Nature

      drug effects, Neovascularization, Physiologic, pathology, drug therapy, Neovascularization, Pathologic, blood supply, Neoplasms, Humans, Drug Resistance, Neoplasm, physiology, Bone Marrow Cells, cytology, Blood Vessels, Animals

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          Abstract

          The growth of blood vessels (a process known as angiogenesis) is essential for organ growth and repair. An imbalance in this process contributes to numerous malignant, inflammatory, ischaemic, infectious and immune disorders. Recently, the first anti-angiogenic agents have been approved for the treatment of cancer and blindness. Angiogenesis research will probably change the face of medicine in the next decades, with more than 500 million people worldwide predicted to benefit from pro- or anti-angiogenesis treatments.

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          Journal
          10.1038/nature04478
          16355210

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