Working largely independently, numerous investigators have explored the role of self-focused attention in various clinical disorders. This article reviews research examining increased self-focused attention in these disorders. Results indicate that regardless of the particular disorder under investigation, a heightened degree of self-focused attention is found. Hence, as ordinarily conceptualized, self-focused attention has little discriminatory power among different psychological disorders. Using information processing constructs, a somewhat different model of self-focused attention is proposed, and it is suggested that certain deviations in this process constitute a psychopathological kind of attention. A meta-construct model of descriptive psychopathology is then outlined to examine how certain aspects of attention can be considered specific to certain disorders and others common to different disorders.