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      Efficacy of pentavalent rotavirus vaccine against severe rotavirus gastroenteritis in infants in developing countries in sub-Saharan Africa: a randomised, double-blind, placebo-controlled trial.

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          Abstract

          Rotavirus gastroenteritis causes many deaths in infants in sub-Saharan Africa. Because rotavirus vaccines have proven effective in developed countries but had not been tested in developing countries, we assessed efficacy of a pentavalent rotavirus vaccine against severe disease in Ghana, Kenya, and Mali between April, 2007, and March, 2009.

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          Author and article information

          Journal
          Lancet
          Lancet (London, England)
          Elsevier BV
          1474-547X
          0140-6736
          Aug 21 2010
          : 376
          : 9741
          Affiliations
          [1 ] Noguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana.
          Article
          S0140-6736(10)60889-6
          10.1016/S0140-6736(10)60889-6
          20692030
          e638c797-5add-4381-a62f-31e3ffd05225
          Copyright 2010 Elsevier Ltd. All rights reserved.
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