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      Holographic Interferometry of Excimer-Laser-Ablated Bovine Eyes: First Results

      a , a , b

      Ophthalmologica

      S. Karger AG

      Excimer laser ablation, Biomechanics, Cornea

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          Abstract

          Purpose: To investigate the effects of areal corneal ablations of different depth on the biomechanical properties of the cornea. Method: The qualitative change of the holographic interferometric fringe pattern of enucleated bovine corneas due to areal mechanical ablations (group A) of 35% and 70% depth of the central cornea and 15, 30, and 50% excimer laser ablations in each eye (group B) was investigated. Results: Ablations of 50% (group B) and 70% (group A) showed a significant variation of the fringe pattern as an effect of the corneal weakening. 15% excimer laser ablations of 5 mm diameter did not result in noticeable changes of the fringe pattern. Half of the 30% ablated corneas in group B showed newly appearing fringes within the area of ablation, indicating a local reduction of the corneal stiffness after ablation. Conclusion: The thickness of the remaining tissue is very important for the biomechanical behavior of the cornea after areal ablations. There are interindividual differences regarding the change of material properties due to excimer laser ablation of 30% depth of ablation.

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          Iatrogenic keratectasia after laser in situ keratomileusis for less than −4.0 to −7.0 diopters of myopia

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            Author and article information

            Journal
            OPH
            Ophthalmologica
            10.1159/issn.0030-3755
            Ophthalmologica
            S. Karger AG
            0030-3755
            1423-0267
            2003
            February 2003
            06 February 2003
            : 217
            : 1
            : 62-67
            Affiliations
            aUniversity Eye Hospital, Münster, Germany; bWroclaw University of Technology, Wroclaw, Poland
            Article
            68241 Ophthalmologica 2003;217:62–67
            10.1159/000068241
            12566876
            © 2003 S. Karger AG, Basel

            Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

            Page count
            Figures: 8, Tables: 1, References: 12, Pages: 6
            Categories
            Original Paper

            Vision sciences, Ophthalmology & Optometry, Pathology

            Cornea, Excimer laser ablation, Biomechanics

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