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      Epidural analgesia and perioperative kidney function after major liver resection.

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          Abstract

          Epidural analgesia (EDA) is a common analgesia regimen in liver resection, and is accompanied by sympathicolysis, peripheral vasodilatation and hypotension in the context of deliberate intraoperative low central venous pressure. This associated fall in mean arterial pressure may compromise renal blood pressure autoregulation and lead to acute kidney injury (AKI). This study investigated whether EDA is a risk factor for postoperative AKI after liver surgery.

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          Author and article information

          Journal
          Br J Surg
          The British journal of surgery
          1365-2168
          0007-1323
          Jun 2015
          : 102
          : 7
          Affiliations
          [1 ] Department of Surgery, Swiss Hepatopancreatobiliary and Transplantation Center, Zurich, Switzerland.
          Article
          10.1002/bjs.9810
          25877255
          © 2015 BJS Society Ltd Published by John Wiley & Sons Ltd.

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