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      Microchannel Deformation of Polymer Chip in In-Mold Bonding


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          Microchannel deformation is a problem which often occurs in the thermal bonding of polymer microfluidic chip, and which is significantly determined by bonding parameters. In this paper, numerical analysis of the microchannel deformation in the process of in-mold bonding polymer chip was conducted, using Young's modulus and shear relaxation modulus of polymethylmethacrylate (PMMA) obtained in creep tests. Adhesion between the top and two lateral walls of microchannel was observed in the results, which can be attributed mainly to the viscoelastic deformation of PMMA. It was also revealed that the maximum percent deformation of microchannel is in height, and that bonding temperature had greater effect on the deformation of microchannel than bonding pressure and bonding time. The deformation of microchannel in simulation were consistent with those of experiment under the optimized parameters of 105 °C, 2 MPa and 240 s.

          Most cited references14

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          Polymer microfabrication technologies for microfluidic systems.

          Polymers have assumed the leading role as substrate materials for microfluidic devices in recent years. They offer a broad range of material parameters as well as material and surface chemical properties which enable microscopic design features that cannot be realised by any other class of materials. A similar range of fabrication technologies exist to generate microfluidic devices from these materials. This review will introduce the currently relevant microfabrication technologies such as replication methods like hot embossing, injection molding, microthermoforming and casting as well as photodefining methods like lithography and laser ablation for microfluidic systems and discuss academic and industrial considerations for their use. A section on back-end processing completes the overview.
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            Micro total analysis systems. Latest advancements and trends.

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              BioMEMS: state-of-the-art in detection, opportunities and prospects.

              In recent years, the biological and biomedical applications of micro- and nanotechnology (commonly referred to as Biomedical or Biological Micro-Electro-Mechanical Systems [BioMEMS]) have become increasingly prevalent and have found widespread use in a wide variety of applications such as diagnostics, therapeutics, and tissue engineering. While research and development activity in this field stays intense, some applications have also been commercialized. This article reviews the recent advances in this very exciting and important field and presents a summary of the state of the art in the area of BioMEMS focusing on diagnostics, sensing, and detection. The areas of therapeutics and hybrid bio/artificial devices will be presented in more detail elsewhere [Biomedical Nanotechnology, Vol. I-IV, Maruo Ferrari (Ed.), Kluwer Academic Publishers, 2004, in press.] and here are discussed briefly in terms of future directions and prospects.

                Author and article information

                International Polymer Processing
                Carl Hanser Verlag
                29 April 2014
                : 29
                : 2
                : 245-251
                1 State Key Laboratory of High Performance Complex Manufacturing, College of Mechanical and Electrical Engineering, Central South University, Changsha, PRC
                Author notes
                [* ] Correspondence address Mail address: Bingyan Jiang, State Key Laboratory of High Performance Complex Manufacturing, College of Mechanical and Electrical Engineering, Central South University, Changsha 410083, PRC E-mail: jby@ 123456csu.edu.cn
                © 2014, Carl Hanser Verlag, Munich
                : 15 July 2013
                : 15 December 2013
                Page count
                References: 14, Pages: 7
                Self URI (journal page): http://www.hanser-elibrary.com/loi/ipp
                Regular Contributed Articles

                Polymer science,Materials technology,Materials characterization,General engineering,Polymer chemistry


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