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      A Pneumonia Diagnosis Scheme Based on Hybrid Features Extracted from Chest Radiographs Using an Ensemble Learning Algorithm

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          Abstract

          Pneumonia is a fatal disease responsible for almost one in five child deaths worldwide. Many developing countries have high mortality rates due to pneumonia because of the unavailability of proper and timely diagnostic measures. Using machine learning-based diagnosis methods can help to detect the disease early and in less time and cost. In this study, we proposed a novel method to determine the presence of pneumonia and identify its type (bacterial or viral) through analyzing chest radiographs. We performed a three-class classification based on features containing diverse information of the samples. After using an augmentation technique to balance the dataset's sample sizes, we extracted the chest X-ray images' statistical features, as well as global features by employing a deep learning architecture. We then combined both sets of features and performed the final classification using the RandomForest classifier. A feature selection method was also incorporated to identify the features with the highest relevance. We tested the proposed method on a widely used (but relabeled) chest radiograph dataset to evaluate its performance. The proposed model can classify the dataset's samples with an 86.30% classification accuracy and 86.03% F-score, which assert the model's efficacy and reliability. However, results show that the classifier struggles while distinguishing between viral and bacterial pneumonia samples. Implementing this method will provide a fast and automatic way to detect pneumonia in a patient and identify its type.

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          Identifying Medical Diagnoses and Treatable Diseases by Image-Based Deep Learning

          The implementation of clinical-decision support algorithms for medical imaging faces challenges with reliability and interpretability. Here, we establish a diagnostic tool based on a deep-learning framework for the screening of patients with common treatable blinding retinal diseases. Our framework utilizes transfer learning, which trains a neural network with a fraction of the data of conventional approaches. Applying this approach to a dataset of optical coherence tomography images, we demonstrate performance comparable to that of human experts in classifying age-related macular degeneration and diabetic macular edema. We also provide a more transparent and interpretable diagnosis by highlighting the regions recognized by the neural network. We further demonstrate the general applicability of our AI system for diagnosis of pediatric pneumonia using chest X-ray images. This tool may ultimately aid in expediting the diagnosis and referral of these treatable conditions, thereby facilitating earlier treatment, resulting in improved clinical outcomes. VIDEO ABSTRACT.
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            CovXNet: A multi-dilation convolutional neural network for automatic COVID-19 and other pneumonia detection from chest X-ray images with transferable multi-receptive feature optimization ☆

            With the recent outbreak of COVID-19, fast diagnostic testing has become one of the major challenges due to the critical shortage of test kit. Pneumonia, a major effect of COVID-19, needs to be urgently diagnosed along with its underlying reasons. In this paper, deep learning aided automated COVID-19 and other pneumonia detection schemes are proposed utilizing a small amount of COVID-19 chest X-rays. A deep convolutional neural network (CNN) based architecture, named as CovXNet, is proposed that utilizes depthwise convolution with varying dilation rates for efficiently extracting diversified features from chest X-rays. Since the chest X-ray images corresponding to COVID-19 caused pneumonia and other traditional pneumonias have significant similarities, at first, a large number of chest X-rays corresponding to normal and (viral/bacterial) pneumonia patients are used to train the proposed CovXNet. Learning of this initial training phase is transferred with some additional fine-tuning layers that are further trained with a smaller number of chest X-rays corresponding to COVID-19 and other pneumonia patients. In the proposed method, different forms of CovXNets are designed and trained with X-ray images of various resolutions and for further optimization of their predictions, a stacking algorithm is employed. Finally, a gradient-based discriminative localization is integrated to distinguish the abnormal regions of X-ray images referring to different types of pneumonia. Extensive experimentations using two different datasets provide very satisfactory detection performance with accuracy of 97.4% for COVID/Normal, 96.9% for COVID/Viral pneumonia, 94.7% for COVID/Bacterial pneumonia, and 90.2% for multiclass COVID/normal/Viral/Bacterial pneumonias. Hence, the proposed schemes can serve as an efficient tool in the current state of COVID-19 pandemic. All the architectures are made publicly available at: https://github.com/Perceptron21/CovXNet.
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              Is Open Access

              A Novel Transfer Learning Based Approach for Pneumonia Detection in Chest X-ray Images

              Pneumonia is among the top diseases which cause most of the deaths all over the world. Virus, bacteria and fungi can all cause pneumonia. However, it is difficult to judge the pneumonia just by looking at chest X-rays. The aim of this study is to simplify the pneumonia detection process for experts as well as for novices. We suggest a novel deep learning framework for the detection of pneumonia using the concept of transfer learning. In this approach, features from images are extracted using different neural network models pretrained on ImageNet, which then are fed into a classifier for prediction. We prepared five different models and analyzed their performance. Thereafter, we proposed an ensemble model that combines outputs from all pretrained models, which outperformed individual models, reaching the state-of-the-art performance in pneumonia recognition. Our ensemble model reached an accuracy of 96.4% with a recall of 99.62% on unseen data from the Guangzhou Women and Children’s Medical Center dataset.
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                Author and article information

                Contributors
                Journal
                J Healthc Eng
                J Healthc Eng
                JHE
                Journal of Healthcare Engineering
                Hindawi
                2040-2295
                2040-2309
                2021
                25 February 2021
                : 2021
                : 8862089
                Affiliations
                1Department of Computer Science, College of Computers and Information Technology, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia
                2Computer Science and Engineering Discipline, Khulna University, Khulna 9208, Bangladesh
                3Electronics and Communication Engineering Discipline, Khulna University, Khulna 9208, Bangladesh
                4Department of Industrial and Systems Engineering, University of Jeddah, P.O. Box: 80327, Jeddah 21589, Saudi Arabia
                5Department of Computer Science and Engineering, Lovely Professional University, Punjab 144411, India
                Author notes

                Academic Editor: Dilbag Singh

                Author information
                https://orcid.org/0000-0001-6019-7245
                https://orcid.org/0000-0003-1639-1301
                https://orcid.org/0000-0003-2391-5767
                https://orcid.org/0000-0002-9016-6105
                https://orcid.org/0000-0002-4433-5529
                https://orcid.org/0000-0003-1179-9092
                https://orcid.org/0000-0003-4915-8426
                Article
                10.1155/2021/8862089
                7935583
                33728035
                e795a96a-813c-4dcb-8743-b67043671e1e
                Copyright © 2021 Mehedi Masud et al.

                This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 4 January 2021
                : 6 February 2021
                : 10 February 2021
                Funding
                Funded by: Taif University
                Award ID: TURSP-2020/10
                Categories
                Research Article

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