Gene expression signature of tolerance and lymphocyte subsets in stable renal transplants: results of a cross-sectional study.

Moreso, Francesc; Torres-Rodríguez, Irina B.; Martínez-Gallo, Mónica; Benlloch, Susana; Cantarell-Aixandri, Carme; Perelló-Carrascosa, Manel; Jimeno, José; Pujol-Borrell, Ricardo; Serón, Daniel

doi:10.1016/j.trim.2014.04.008

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Gene expression signature of tolerance and lymphocyte subsets in stable renal transplants: results of a cross-sectional study.

Author(s): Francesc Moreso ¹ , Irina B Torres ² , Monica Martínez-Gallo ³ , Susana Benlloch ⁴ , Carme Cantarell ² , Manel Perelló ² , José Jimeno ⁴ , Ricardo Pujol-Borrell ³ , Daniel Seron ²

Publication date (Electronic): Jun 2014

Journal: Transplant immunology

Publisher: Elsevier BV

Keywords: B cells, Chronic rejection, Immunosuppression, Lymphocyte subpopulations, Operational tolerance, Renal transplantation

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Abstract

In kidney transplants operational tolerance has been associated with up-regulation of B cell differentiation genes and an increased number of total, naive and transitional peripheral B cells. The aim is to evaluate tolerance biomarkers in different cohorts of stable renal transplants under immunosuppression.

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Journal ID (iso-abbrev): Transpl. Immunol.

Title: Transplant immunology

Publisher: Elsevier BV

ISSN (Electronic): 1878-5492

ISSN (Print): 0966-3274

Publication date (Electronic): Jun 2014

Volume: 31

Issue: 1

Affiliations

[1 ] Nephrology Department, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain. Electronic address: fjmoreso@vhebron.net.

[2 ] Nephrology Department, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain.

[3 ] Immunology Department, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Spain.

[4 ] Pangaea Biotech S.L., Spain.

Article

Publisher Item ID: S0966-3274(14)00031-8

DOI: 10.1016/j.trim.2014.04.008

PubMed ID: 24810779

SO-VID: e7d7e6f7-6bc3-49bf-b721-ac7657644984

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Keywords: B cells,Chronic rejection,Immunosuppression,Lymphocyte subpopulations,Operational tolerance,Renal transplantation

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Keywords: B cells, Chronic rejection, Immunosuppression, Lymphocyte subpopulations, Operational tolerance, Renal transplantation

Gene expression signature of tolerance and lymphocyte subsets in stable renal transplants: results of a cross-sectional study.

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