Appendicectomy for suspected uncomplicated appendicitis is associated with fewer complications than conservative antibiotic management: a meta-analysis of post-intervention complications.

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Abstract

Recent literature has concluded antibiotic therapy results in fewer complications than appendicectomy for patients with uncomplicated appendicitis. This studies aim was to undertake a meta-analysis of major post-intervention outcomes in patients with suspected uncomplicated appendicitis treated with antibiotics or appendicectomy, and determine which treatment is associated with the lowest rate of major complications.

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Author and article information

Journal

Journal ID (iso-abbrev): J. Infect.

Title: The Journal of infection

ISSN (Electronic): 1532-2742

ISSN (Print): 0163-4453

Publication date (Electronic): Feb 2015

Volume: 70

Issue: 2

Affiliations

[1 ] The Department of Microbiology, Old Medical School, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Leeds LS1 3EX, England, UK; Leeds Institute of Biomedical and Clinical Sciences, Old Medical School, The University of Leeds, Leeds General Infirmary, Leeds LS1 3EX, England, UK. Electronic address: a.kirby@leeds.ac.uk.

[2 ] The Department of Microbiology, Old Medical School, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Leeds LS1 3EX, England, UK; Leeds Institute of Biomedical and Clinical Sciences, Old Medical School, The University of Leeds, Leeds General Infirmary, Leeds LS1 3EX, England, UK. Electronic address: Richard.Hobson@leedsth.nhs.uk.

[3 ] The Department of Surgery, Lincoln Wing, St. James's University Hospital, Leeds Teaching Hospitals NHS Trust, Leeds LS9 7TF, England, UK; Leeds Institute of Biomedical and Clinical Sciences, Clinical Sciences Building, The University of Leeds, St. James's University Hospital, Leeds LS9 7TF, England, UK. Electronic address: d.burke@leeds.ac.uk.

[4 ] Leeds Institute of Biomedical and Clinical Sciences, Old Medical School, The University of Leeds, Leeds General Infirmary, Leeds LS1 3EX, England, UK. Electronic address: um12vc@leeds.ac.uk.

[5 ] Leeds Institute of Biomedical and Clinical Sciences, Old Medical School, The University of Leeds, Leeds General Infirmary, Leeds LS1 3EX, England, UK. Electronic address: um12gmf@leeds.ac.uk.

[6 ] Charles Thackrah Building, Leeds Institute of Health Sciences, The University of Leeds, LS2 9LJ, UK. Electronic address: R.M.West@leeds.ac.uk.

Article

Publisher Item ID: S0163-4453(14)00269-2

DOI: 10.1016/j.jinf.2014.08.009

PubMed ID: 25175926

SO-VID: e7f003ca-2219-4923-95fc-aa917b2d58a2

History

Keywords: Antimicrobial,Appendicectomy,Appendicitis

Data availability:

Keywords: Antimicrobial, Appendicectomy, Appendicitis

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