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      Sulfated Glycosaminoglycan Content of Glomerular and Tubular Basement Membranes of Individuals of Different Ages

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          Abstract

          The glycosaminoglycan content of glomerular and tubular basement membranes in individuals ranging from preterm neonates to 90-years-old people was determined with a spectrophotometric assay after papain digestion. A decrease of glycosaminoglycans until the age of 2.5 years was observed only in glomerular basement membrane. Tubular basement membranes did not show significant changes with age. Glomerular basement membranes of neonates had a higher glycosaminoglycan content than tubular basement membranes.

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          Author and article information

          Journal
          NEF
          Nephron
          10.1159/issn.1660-8151
          Nephron
          S. Karger AG
          1660-8151
          2235-3186
          1985
          1985
          04 December 2008
          : 41
          : 4
          : 344-347
          Affiliations
          Departments of aBiochemistry and bPaediatrics, University of Nijmegen, Nijmegen, The Netherlands
          Article
          183612 Nephron 1985;41:344–347
          10.1159/000183612
          3934573
          © 1985 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 4
          Categories
          Original Paper

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