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      Leiomyosarcoma of the renal vein

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          Abstract

          Leiomyosarcoma of the renal vein is a rare tumor of complex diagnosis. We presented a case of renal vein leiomyosarcoma detected in a routine study. The primary treatment was complete surgical removal of the mass. In cases where surgical removal is not possible the prognosis is poor, with high rates of local recurrence and distant spread.

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          Prognostic factors in primary retroperitoneal soft-tissue sarcomas.

          We analyzed independent treatment variables (age, sex, signs and symptoms, site, size, histopathologic findings, grade, and clinical presentation) and treatment-dependent variables (resectability, type of operation, surgical margins, surgical boundaries, microscopic margins, adjuvant radiotherapy, and adjuvant chemotherapy) in 80 patients with primary retroperitoneal soft-tissue sarcomas admitted from 1982 through 1988. Both univariate and multivariate analysis of survival and disease-free survival were performed. The major factor in survival outcome was the ability to completely resect the lesion. When the 62 patients who underwent complete resection were examined, the only independent prognostic factor for both survival and disease-free survival was grade. We conclude that completeness of resection and grade of the lesion are primary determinants of survival. Once all tumor is macroscopically removed, no advantage could be demonstrated by more extensive surgical resection or current adjuvant therapy.
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            Leiomyosarcoma of the renal vein.

            The preoperative diagnosis for primary leiomyosarcoma of the renal vein, an extremely rare tumor, is difficult. The tumor predominantly occurs in women and on the left side. Its natural history is toward distant metastases and a poor 5-year survival rate. Nephrectomy and en-bloc surgical resection remain the mainstay of therapy. We present three such cases and review the world literature.
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              Primary renal vein leiomyosarcoma

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                Author and article information

                Journal
                ibju
                International braz j urol
                Int. braz j urol.
                Sociedade Brasileira de Urologia (Rio de Janeiro, RJ, Brazil )
                1677-5538
                1677-6119
                February 2003
                : 29
                : 1
                : 43-44
                Affiliations
                [01] São Paulo SP orgnameAlbert Einstein Jewish Hospital
                Article
                S1677-55382003000100009 S1677-5538(03)02900109
                10.1590/S1677-55382003000100009
                e825278f-cf67-4b99-9e8f-3bb4925b35b0

                This work is licensed under a Creative Commons Attribution 4.0 International License.

                History
                : 12 August 2002
                : 09 January 2003
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 3, Pages: 2
                Product

                SciELO Brazil

                Categories
                Case Report

                leiomyosarcoma,muscle neoplasms,renal veins,kidney
                leiomyosarcoma, muscle neoplasms, renal veins, kidney

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