1,129
views
0
recommends
+1 Recommend
0 collections
    20
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Circos: an information aesthetic for comparative genomics.

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          We created a visualization tool called Circos to facilitate the identification and analysis of similarities and differences arising from comparisons of genomes. Our tool is effective in displaying variation in genome structure and, generally, any other kind of positional relationships between genomic intervals. Such data are routinely produced by sequence alignments, hybridization arrays, genome mapping, and genotyping studies. Circos uses a circular ideogram layout to facilitate the display of relationships between pairs of positions by the use of ribbons, which encode the position, size, and orientation of related genomic elements. Circos is capable of displaying data as scatter, line, and histogram plots, heat maps, tiles, connectors, and text. Bitmap or vector images can be created from GFF-style data inputs and hierarchical configuration files, which can be easily generated by automated tools, making Circos suitable for rapid deployment in data analysis and reporting pipelines.

          Related collections

          Author and article information

          Journal
          Genome Res
          Genome research
          Cold Spring Harbor Laboratory
          1549-5469
          1088-9051
          Sep 2009
          : 19
          : 9
          Affiliations
          [1 ] Canada's Michael Smith Genome Sciences Center, Vancouver, British Columbia V5Z 4S6, Canada. martink@bcgsc.ca
          Article
          gr.092759.109
          10.1101/gr.092759.109
          2752132
          19541911
          e8c9ce75-78ff-45eb-97b2-90339014df98
          History

          Comments

          Comment on this article