Widespread adoption of point-of-care resistance diagnostics (POCRD) reduces ineffective
antibiotic use but could increase overall antibiotic use. Indeed, in the context of
a standard susceptible-infected epidemiological model with a single antibiotic, POCRD
accelerates the rise of resistance in the disease-causing bacterial population. When
multiple antibiotics are available, however, POCRD may slow the rise of resistance
even as more patients receive antibiotic treatment, belying the conventional wisdom
that antibiotics are "exhaustible resources" whose increased use necessarily promotes
the rise of resistance.