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Overview and Findings from the Religious Orders Study
June 01 2012
June 01 2012
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Abstract
The Religious Orders Study is a longitudinal clinical-pathologic cohort study of aging
and Alzheimer's disease (AD). In this manuscript, we summarize the study methods including
the study design and describe the clinical evaluation, assessment of risk factors,
collection of ante-mortem biological specimens, brain autopsy and collection of selected
postmortem data.
(1) review the relation of neuropathologic indices to clinical diagnoses and cognition
proximate to death; (2) examine the relation of risk factors to clinical outcomes;
(3) examine the relation of risk factors to measures of neuropathology; and (4) summarize
additional study findings. We then discuss and contextualize the study findings.