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      Investigation of Suspected Pulmonary Embolism at Hutt Valley Hospital with CT Pulmonary Angiography: Current Practice and Opportunities for Improvement

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      Advances in Medicine
      Hindawi Publishing Corporation

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          Abstract

          Aims. To study the use of CT pulmonary angiography (CTPA) at Hutt Hospital and investigate the use of pretest probability scoring in the assessment of patients with suspected pulmonary embolism (PE). Methods. We studied patients with suspected PE that underwent CTPA between January and May 2012 and collected data on demographics, use of pretest probability scoring, and use of D Dimer and compared our practice with the British Thoracic Society (BTS) guideline. Results. 105 patients underwent CTPA and 15% of patients had PE. 13% of patients had a Wells score prior to their scan. Wells score calculated by researchers revealed 54%, 36%, and 8% patients had low, medium, and high risk pretest probabilities and 8%, 20%, and 50% of these patients had positive scans. D Dimer was performed in 58% of patients and no patients with a negative D Dimer had a PE. Conclusion. The CTPA positive rate was similar to other contemporary studies but lower than previous New Zealand studies and some international guidelines. Risk stratification of suspected PE using Wells score and D Dimer was underutilised. A number of scans could have been safely avoided by using accepted guidelines reducing resources use and improving patient safety.

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          Most cited references13

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          Prediction of pulmonary embolism in the emergency department: the revised Geneva score.

          Diagnosis of pulmonary embolism requires clinical probability assessment. Implicit assessment is accurate but is not standardized, and current prediction rules have shortcomings. To construct a simple score based entirely on clinical variables and independent from physicians' implicit judgment. Derivation and external validation of the score in 2 independent management studies on pulmonary embolism diagnosis. Emergency departments of 3 university hospitals in Europe. Consecutive patients admitted for clinically suspected pulmonary embolism. Collected data included demographic characteristics, risk factors, and clinical signs and symptoms suggestive of venous thromboembolism. The variables statistically significantly associated with pulmonary embolism in univariate analysis were included in a multivariate logistic regression model. Points were assigned according to the regression coefficients. The score was then externally validated in an independent cohort. The score comprised 8 variables (points): age older than 65 years (1 point), previous deep venous thrombosis or pulmonary embolism (3 points), surgery or fracture within 1 month (2 points), active malignant condition (2 points), unilateral lower limb pain (3 points), hemoptysis (2 points), heart rate of 75 to 94 beats/min (3 points) or 95 beats/min or more (5 points), and pain on lower-limb deep venous palpation and unilateral edema (4 points). In the validation set, the prevalence of pulmonary embolism was 8% in the low-probability category (0 to 3 points), 28% in the intermediate-probability category (4 to 10 points), and 74% in the high-probability category (> or =11 points). Interobserver agreement for the score items was not studied. The proposed score is entirely standardized and is based on clinical variables. It has sustained internal and external validation and should now be tested for clinical usefulness in an outcome study.
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            British Thoracic Society guidelines for the management of suspected acute pulmonary embolism.

            (2003)
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              Contrast media and the kidney: European Society of Urogenital Radiology (ESUR) guidelines.

              The Contrast Media Safety Committee of the European Society of Urogenital Radiology (ESUR) has looked at the effects of contrast media on the kidney including prevention of contrast medium induced nephropathy. This has resulted in four reports dealing with 1) contrast medium induced nephrotoxicity, 2) haemodialysis and contrast media, 3) use of gadolinium contrast media instead of iodinated contrast media and 4) contrast media injection in diabetic patients receiving metformin. The review presents an overview of these four reports and offers the current understanding of the interaction between contrast agents and the kidney.
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                Author and article information

                Journal
                Adv Med
                Adv Med
                AMED
                Advances in Medicine
                Hindawi Publishing Corporation
                2356-6752
                2314-758X
                2015
                1 March 2015
                : 2015
                : 357576
                Affiliations
                Hutt Valley District Health Board, Lower Hutt, Wellington 5040, New Zealand
                Author notes
                *Sisira Jayathissa: sjay1@ 123456xtra.co.nz

                Academic Editor: Hiromichi Suzuki

                Article
                10.1155/2015/357576
                4590957
                26556556
                e91cb16f-41ab-4b52-828c-decad57f6c80
                Copyright © 2015 Nick Kennedy et al.

                This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 1 July 2014
                : 18 February 2015
                Categories
                Clinical Study

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