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      Economic evaluation of a mentorship and enhanced supervision program to improve quality of integrated management of childhood illness care in rural Rwanda

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          Abstract

          Background

          Integrated management of childhood illness (IMCI) can reduce under-5 morbidity and mortality in low-income settings. A program to strengthen IMCI practices through Mentorship and Enhanced Supervision at Health centers (MESH) was implemented in two rural districts in eastern Rwanda in 2010.

          Methods

          We estimated cost per improvement in quality of care as measured by the difference in correct diagnosis and correct treatment at baseline and 12 months of MESH. Costs of developing and implementing MESH were estimated in 2011 United States Dollars (USD) from the provider perspective using both top-down and bottom-up approaches, from programmatic financial records and site-level data. Improvement in quality of care attributed to MESH was measured through case management observations (n = 292 cases at baseline, 413 cases at 12 months), with outcomes from the intervention already published. Sensitivity analyses were conducted to assess uncertainty under different assumptions of quality of care and patient volume.

          Results

          The total annual cost of MESH was US$ 27,955.74 and the average cost added by MESH per IMCI patient was US$1.06. Salary and benefits accounted for the majority of total annual costs (US$22,400 /year). Improvements in quality of care after 12 months of MESH implementation cost US$2.95 per additional child correctly diagnosed and $5.30 per additional child correctly treated.

          Conclusions

          The incremental costs per additional child correctly diagnosed and child correctly treated suggest that MESH could be an affordable method for improving IMCI quality of care elsewhere in Rwanda and similar settings. Integrating MESH into existing supervision systems would further reduce costs, increasing potential for spread.

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          Most cited references26

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          Integrated management of childhood illness by outpatient health workers: technical basis and overview. The WHO Working Group on Guidelines for Integrated Management of the Sick Child.

          S Gove (1997)
          This article describes the technical basis for the guidelines for the integrated management of childhood illness (IMCI), which are presented in the WHO/UNICEF training course on IMCI for outpatient health workers at first-level health facilities in developing countries. These guidelines include the most important case management and preventive interventions against the leading causes of childhood mortality--pneumonia, diarrhoea, malaria, measles and malnutrition. The training course enables health workers who use the guidelines to make correct decisions in the management of sick children. The guidelines have been refined through research studies and field-testing in the Gambia, Ethiopia, Kenya, and United Republic of Tanzania, as well as studies on clinical signs in the detection of anaemia and malnutrition. These studies, and two others from Uganda and Bangladesh, are presented in this Supplement to the Bulletin of the World Health Organization.
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            Programmatic pathways to child survival: results of a multi-country evaluation of Integrated Management of Childhood Illness.

            To summarize the expectations held by World Health Organization programme personnel about how the introduction of the Integrated Management of Childhood Illness (IMCI) strategy would lead to improvements in child health and nutrition, to compare these expectations with what was learned from the Multi-Country Evaluation of IMCI Effectiveness, Cost and Impact (MCE-IMCI), and to discuss the implications of these findings for child survival policies and programmes. The MCE-IMCI study designs were based on an impact model developed in 1999-2000 to define how IMCI would be implemented at country level and below, and the outcomes and impact it would have on child health and survival. MCE-IMCI studies included: feasibility assessments documenting IMCI implementation in 12 countries (1999-2001); in-depth studies using compatible designs in Bangladesh, Brazil, Peru, Tanzania and Uganda; and cross-site analyses addressing the effectiveness of specific subsets of IMCI activities. The IMCI strategy was successfully introduced in the great majority of countries with moderate to high levels of child mortality in the period from 1996 to 2001. Seven years of country-based evaluation, however, indicates that some of the basic expectations underlying the development of IMCI were not met. Four of the five countries (the exception is Tanzania) had difficulties in expanding the strategy at national level while maintaining adequate intervention quality. Technical guidelines on delivering interventions at family and community levels were slow to appear, and in their absence countries stalled in their efforts to increase population coverage with essential interventions related to care-seeking, nutrition, and correct care of the sick child at home. The full weight of health system limitations on IMCI implementation was not appreciated at the outset, and only now is it clear that solutions to larger problems in political commitment, human resources, financing, integrated or at least coordinated programme management, and effective decentralization are essential underpinnings of successful efforts to reduce child mortality. This analysis highlights the need for a shift if child survival efforts are to be successful. Delivery systems that rely solely on government health facilities must be expanded to include the full range of potential channels in a setting and strong community-based approaches. The focus on process within child health programmes must change to include greater accountability for intervention coverage at population level. Global strategies that expect countries to make massive adaptations must be complemented by country-level implementation guidelines that begin with local epidemiology and rely on tools developed for specific epidemiological profiles.
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              Effectiveness and cost of facility-based Integrated Management of Childhood Illness (IMCI) in Tanzania.

              The Integrated Management of Childhood Illness (IMCI) strategy is designed to address major causes of child mortality at the levels of community, health facility, and health system. We assessed the effectiveness of facility-based IMCI in rural Tanzania. We compared two districts with facility-based IMCI and two neighbouring comparison districts without IMCI, from 1997 to 2002, in a non-randomised study. We assessed quality of case-management for children's illness, drug and vaccine availability, and supervision involving case-management, through a health-facility survey in 2000. Household surveys were used to assess child-health indicators in 1999 and 2002. Survival of children was tracked through demographic surveillance over a predefined 2-year period from mid 2000. Further information on contextual factors was gathered through interviews and record review. The economic cost of health care for children in IMCI and comparison districts was estimated through interviews and record review at national, district, facility, and household levels. During the IMCI phase-in period, mortality rates in children under 5 years old were almost identical in IMCI and comparison districts. Over the next 2 years, the mortality rate was 13% lower in IMCI than in comparison districts (95% CI -7 to 30 or 5 to 21, depending on how adjustment is made for district-level clustering), with a rate difference of 3.8 fewer deaths per 1000 child-years. Contextual factors, such as use of mosquito nets, all favoured the comparison districts. Costs of children's health care with IMCI were similar to or lower than those for case-management without IMCI. Our findings indicate that facility-based IMCI is good value for money, and support widespread implementation in the context of health-sector reform, basket funding, good facility access, and high utilisation of health facilities.
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                Author and article information

                Contributors
                Role: ConceptualizationRole: MethodologyRole: SupervisionRole: Writing – original draft
                Role: ConceptualizationRole: Formal analysis
                Role: ConceptualizationRole: Formal analysis
                Role: Writing – original draft
                Role: Writing – review & editing
                Role: ConceptualizationRole: SupervisionRole: Writing – review & editing
                Role: Editor
                Journal
                PLoS One
                PLoS ONE
                plos
                plosone
                PLoS ONE
                Public Library of Science (San Francisco, CA USA )
                1932-6203
                16 March 2018
                2018
                : 13
                : 3
                : e0194187
                Affiliations
                [1 ] University of Rwanda, College of Medicine and Health Sciences; Kigali, Rwanda
                [2 ] Partners In Health; Kigali; Rwanda and Boston, United States of America
                [3 ] Division of Global Health Equity, Brigham and Women’s Hospital; Boston, United States of America
                [4 ] Department of Epidemiology, Harvard T. H. Chan School of Public Health; Boston, United States of America
                [5 ] Division of General Pediatrics, Boston Children’s Hospital; Boston, United States of America
                [6 ] Rwanda Ministry of Health; Kigali, Rwanda
                [7 ] Department of Global Health and Social Medicine, Harvard Medical School; Boston, United States of America
                [8 ] Ariadne Labs, Boston, United States of America
                University of Waterloo, CANADA
                Author notes

                Competing Interests: The authors have declared that no competing interests exist.

                Author information
                http://orcid.org/0000-0003-4563-9855
                Article
                PONE-D-16-33383
                10.1371/journal.pone.0194187
                5856263
                29547624
                e91dcaa6-3ebf-4b43-a7df-8cb06f2a5420
                © 2018 Manzi et al

                This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

                History
                : 20 August 2016
                : 19 February 2018
                Page count
                Figures: 1, Tables: 4, Pages: 12
                Funding
                Funded by: African Health Initiative of the Doris Duke Charitable Foundation
                Award ID: 2009057
                This work was supported by the African Health Initiative of the Doris Duke Charitable Foundation in Rwanda (2009057). The funder provided support in the form of salaries for authors AM, HSI and LRH but did not have any additional role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. The specific roles of these authors are articulated in the ‘author contributions’ section. There was no additional external funding received for this study and no commercial entities involved.
                Categories
                Research Article
                Medicine and Health Sciences
                Health Care
                Quality of Care
                People and Places
                Population Groupings
                Professions
                Medical Personnel
                Nurses
                Medicine and Health Sciences
                Health Care
                Health Care Providers
                Nurses
                Social Sciences
                Economics
                Economic Analysis
                Cost-Effectiveness Analysis
                Medicine and Health Sciences
                Health Care
                Health Services Administration and Management
                Medicine and Health Sciences
                Health Care
                Health Care Policy
                Health Systems Strengthening
                People and Places
                Geographical Locations
                Africa
                Rwanda
                Social Sciences
                Economics
                Finance
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                Labor Economics
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                Custom metadata
                Data are from the Partners In Health's Mentorship and Quality Improvement Program's financial and monitoring and evaluation database whose access can be guaranteed through its research committee at IMBRC@ 123456pih.org .

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