Somatotropic-Testicular Axis: A crosstalk between GH/IGF-I and gonadal hormones during development, transition, and adult age.

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Abstract

The hypothalamic-pituitary-gonadal (HPG) and hypothalamic-pituitary-somatotropic (HPS) axes are strongly interconnected. Interactions between these axes are complex and poorly understood. These interactions are characterized by redundancies in reciprocal influences at each level of regulation and the combination of endocrine and paracrine effects that change during development.

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Journal

Journal ID (iso-abbrev): Andrology

Title: Andrology

Publisher: Wiley

ISSN (Electronic): 2047-2927

ISSN (Print): 2047-2919

Publication date (Electronic): January 2021

Volume: 9

Issue: 1

Affiliations

[1 ] Department of Experimental Medicine, Sapienza University, Rome, Italy.

[2 ] Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.

[3 ] Athens Naval and Veterans Affairs Hospital, Athens, Greece.

[4 ] Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, Florence, Italy.

Article

DOI: 10.1111/andr.12918

PubMed ID: 33021069

SO-VID: e942fb9c-9034-43a9-9401-3582d7498b2b

History

Keywords: IGF-I,growth hormone,growth hormone deficiency,puberty,testicle,transition age

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Keywords: IGF-I, growth hormone, growth hormone deficiency, puberty, testicle, transition age

Somatotropic-Testicular Axis: A crosstalk between GH/IGF-I and gonadal hormones during development, transition, and adult age.

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Karger: Endocrinology

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