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      Nontraumatic bladder rupture: The images before and after

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          Abstract

          We should consider the complication of bladder rupture for patients with worsened abdominal pain and inability to pass urine following acute cystitis. A CT scan is a useful first‐line modality when evaluating for a suspected bladder rupture.

          Abstract

          We should consider the complication of bladder rupture for patients with worsened abdominal pain and inability to pass urine following acute cystitis. A CT scan is a useful first‐line modality when evaluating for a suspected bladder rupture.

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          Extraperitoneal Rupture of a Bladder Diverticulum and the Role of Multidetector Computed Tomography Cystography

          Nontraumatic rupture of the bladder is less widely recognized than traumatic rupture, with a challenging early diagnosis due to high variability in clinical presentations. We report a case of extraperitoneal rupture of a bladder diverticulum in a patient with diabetes mellitus who presented with paralytic ileus. Despite conservative management, the patient developed sepsis requiring surgical treatment. Urinary tract infection and bladder outlet obstruction were considered to be potential mechanisms of the rupture. Multidetector computed tomography cystography should be used as the first-line modality when evaluating for a suspected bladder rupture, even in patients with nontraumatic bladder rupture.
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            Effects of prepubertal corticosterone treatment on urinary bladder

            PURPOSE: The aim of this work was to analyze the bladder wall modifications after a chronic treatment with high doses of corticosterone in prepubertal rats. METHODS: This study included 26 male rats assigned into four groups: T30 was treated with corticosterone until 29 days of age and killed at day 30, while T65 group received the same treatment but was killed at day 65. Each group had its own control group (C30 and C65). For treated animals, daily intraperitoneal injections of corticosterone (20 mg/Kg) were administered between 7th and 29th day of life. Bladders were removed and collagen, smooth muscle, elastic fibers system, vascular density and epithelium were analyzed by morphometrical methods, immunofluorescence, and biochemistry. RESULTS: Vascular density in lamina propria was reduced by 40% (p<0.05) in group T65. Collagen organization was altered in T30 and T65, although total collagen concentration was unchanged. The T65 group had an increase in elastic system fibers. There was no difference in epithelial height and cell density between the groups. Concerning the smooth muscle fibers density we observed a 19% increase (p<0.05) in the T65 group. CONCLUSION: Prepubertal administration of corticosterone induces structural modifications in the bladder of rats in a medium term analysis.
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              Author and article information

              Contributors
              mokano@med.kobe-u.ac.jp
              Journal
              Clin Case Rep
              Clin Case Rep
              10.1002/(ISSN)2050-0904
              CCR3
              Clinical Case Reports
              John Wiley and Sons Inc. (Hoboken )
              2050-0904
              10 June 2021
              June 2021
              : 9
              : 6 ( doiID: 10.1002/ccr3.v9.6 )
              : e04312
              Affiliations
              [ 1 ] Division of General Internal Medicine Department of Internal Medicine Kobe University Graduate School of Medicine Kobe Japan
              Author notes
              [*] [* ] Correspondence

              Mitsumasa Okano, Division of General Internal Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7‐5‐1, Kusunoki‐cho, Chuo‐ku, Kobe 650‐0017, Japan.

              Email: mokano@ 123456med.kobe-u.ac.jp

              Author information
              https://orcid.org/0000-0002-2323-5086
              Article
              CCR34312
              10.1002/ccr3.4312
              8190686
              34136244
              e9fecf10-8953-4a3d-846a-6c23502016d4
              © 2021 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.

              This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

              History
              : 15 February 2021
              : 12 November 2020
              : 28 April 2021
              Page count
              Figures: 2, Tables: 0, Pages: 0, Words: 570
              Categories
              Clinical Image
              Clinical Images
              Custom metadata
              2.0
              June 2021
              Converter:WILEY_ML3GV2_TO_JATSPMC version:6.0.2 mode:remove_FC converted:10.06.2021

              acute cystitis,bladder diverticulum,bladder rupture,ct scan,retrograde cystography

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