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      Abdominal Vagotomy Does Not Activate the Corpus luteum in Rats

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          Abstract

          Rats were vagotomized at proestrus and 4 days later serum prolactin and progesterone were determined by radioimmunoassay. The histology of the ovaries and the activity of ovarian Δ<sup>5–</sup>3β-hydroxysteroid dehydrogenase (3β-HSD) were also studied. There was no difference between hormone values in sham and vagotomized rats 4 days after surgery. In addition, the ovarian histology and activity of 3β-HSD were similar in both sham and vagotomized animals. We conclude that vagotomy at proestrus does not interrupt estrous cycles by activating the corpus luteum.

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          Author and article information

          Journal
          NEN
          Neuroendocrinology
          10.1159/issn.0028-3835
          Neuroendocrinology
          S. Karger AG
          0028-3835
          1423-0194
          1983
          1983
          27 March 2008
          : 37
          : 4
          : 288-290
          Affiliations
          Departments of aAnatomy and bObstetrics and Gynecology, School of Medicine, East Carolina University, Greenville, N.C., USA
          Article
          123561 Neuroendocrinology 1983;37:288–290
          10.1159/000123561
          6579393
          ea16ff3e-0f87-42b3-a793-8718032f47b8
          © 1983 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          : 04 March 1983
          : 22 April 1983
          Page count
          Pages: 3
          Categories
          Original Paper

          Endocrinology & Diabetes,Neurology,Nutrition & Dietetics,Sexual medicine,Internal medicine,Pharmacology & Pharmaceutical medicine
          Δ5–3β Hydroxysteroid dehydrogenase,Progesterone,Estrous cycle,Corpus luteum,Rat,Vagotomy,Prolactin

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