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      Relationship between Ciliary Perfusion Pressure and Pattern-Reversal Visual Evoked Cortical Potentials: An Electro-Encephalo-Dynamographic Investigation


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          Pattern-reversal visual evoked cortical potentials (VECP) taken from 25 healthy volunteers before, during and after short-lasting elevation of intraocular pressure proved to be dependent on ciliary perfusion pressure (pp<sub>cil</sub>) in a characteristic way. Reductions of pp<sub>cil</sub> to ca. 30 mm Hg did not result in VECP changes. These results point to efficient autoregulation in the retinal circulation and in the circulatory region of the anterior part of the optic nerve. When ppcil was reduced to below 30 mm Hg a marked reduction of VECP amplitudes and prolongation of latencies were observed. An autoregulatory capacity of about 15 mm Hg was found.

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          Author and article information

          Ophthalmic Res
          Ophthalmic Research
          S. Karger AG
          04 December 2009
          : 18
          : 5
          : 260-264
          Department of Experimental Ophthalmology, Eye Clinic of the Karl Marx University. Leipzig, GDR
          265444 Ophthalmic Res 1986;18:260–264
          © 1986 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          : 25 June 1986
          : 17 April 1986
          Page count
          Pages: 5
          Original Paper

          Vision sciences,Ophthalmology & Optometry,Pathology
          Electro-encephalo-dynamography,Visual evoked cortical potentials,Autoregulation,Ciliary perfusion pressure


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