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      Lumbosacral spondylodiscitis due to rectal fistula following mesh penetration 7 years after colpopexy

      case-report

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          Highlights

          • Spondylodiscitis by Enterococcus spp. is rare and usually related to direct inoculation to the spine.

          • Previous abdominal implants must be investigated in spondylodiscitis by enteric microorganisms.

          • If spondylodiscitis treatment is unsuccessful, an active infectious focus must be investigated.

          Abstract

          Introduction

          The primary source of spondylodiscitis cannot always be identified. However, not treating the original focus might preclude successful healing due to further spread of the causative microorganisms.

          Case report

          An 80-year-old woman presented with lumbar spondylodiscitis. She received surgical debridement and stabilization with transforaminal lumbar interbody fusion and tailored antibiotic therapy after isolation of Enterococcus spp. Despite appropriate treatment, the patient’s condition continued to worsen. An extensive search for the primary infection source finally revealed a rectal fistula caused by a synthetic mesh that had been inserted 7 years before for abdominal sacrocolpopexy. Only after removal of the fistula and protective ileostomy did the patient’s condition improved, allowing successful healing of the spondylodiscitis. After a follow-up period of one year no infection relapse was observed.

          Conclusion

          In cases of spondyodiscitis that are resistant to adequate treatment, a search for infection source must be continued until the focus is found and treated. The presence of uncommon enteric microorganisms causing spondylodiscitis, such as Enterococcus spp., is suggestive of contiguous spread and should therefore be further investigated.

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          Most cited references15

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          Pyogenic vertebral osteomyelitis: a systematic review of clinical characteristics.

          Vertebral osteomyelitis is a cause of back pain that can lead to neurologic deficits if not diagnosed in time and effectively treated. The objective of this study was to systematically review the clinical characteristics of pyogenic vertebral osteomyelitis (PVO). The authors conducted a systematic review of the English literature. The inclusion criteria included studies with 10 or more subjects diagnosed with PVO based on the combination of clinical presentation with either a definitive bacteriologic diagnosis or pathological and/or imaging studies. The 14 studies that met selection criteria included 1008 patients with PVO. Of them, the majority (62%) were men, with back pain and fever as the most common presenting symptoms. Diabetes mellitus was the most common underlying medical illness, while the urinary tract was the commonest source of infection. Staphylococcus aureus was the most commonly isolated organism. Computed tomographic guided or open biopsy yielded the causative organism more often than blood cultures (77% versus 58%). Plain radiography showed abnormalities in 89% of the cases, while bone scanning and computed tomography or magnetic resonance imaging were positive in 94% of the cases, revealing lumbar as the most commonly affected area. The attributable mortality was 6%, while relapses and neurological deficits were described in the 32% and 32% of the cases, respectively. PVO is an illness of middle-aged individuals with underlying medical illnesses. Although the mortality rate is low, relapses and neurological deficits are common, making early diagnosis a major challenge for the physician.
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            Abdominal sacrocolpopexy: a comprehensive review.

            To summarize published data about abdominal sacrocolpopexy and to highlight areas about which data are lacking. We conducted a literature search on MEDLINE using Ovid and PubMed, from January,1966 to January, 2004, using search terms "sacropexy," "sacrocolpopexy," "sacral colpopexy," "colpopexy," "sacropexy," "colposacropexy," "abdominal sacrocolpopexy" "pelvic organ prolapse and surgery," and "vaginal vault prolapse or surgery" and included articles with English-language abstracts. We examined reference lists of published articles to identify other articles not found on the electronic search. We examined all studies identified in our search that provided any outcome data on sacrocolpopexy. Because of the substantial heterogeneity of outcome measures and follow-up intervals in case studies, we did not apply meta-analytic techniques to the data. Follow-up duration for most studies ranged from 6 months to 3 years. The success rate, when defined as lack of apical prolapse postoperatively, ranged from 78-100% and when defined as no postoperative prolapse, from 58-100%. The median reoperation rates for pelvic organ prolapse and for stress urinary incontinence in the studies that reported these outcomes were 4.4% (range 0-18.2%) and 4.9% (range 1.2% to 30.9%), respectively. The overall rate of mesh erosion was 3.4% (70 of 2,178). Some reports found more mesh erosions when concomitant total hysterectomy was done, whereas other reports did not. There were no data to either support or refute the contentions that concomitant culdoplasty or paravaginal repair decreased the risk of failure. Most authors recommended burying the graft under the peritoneum to attempt to decrease the risk of bowel obstruction; despite this, the median rate (when reported) of small bowel obstruction requiring surgery was 1.1% (range 0.6% to 8.6%). Few studies rigorously assessed pelvic symptoms, bowel function, or sexual function. Sacrocolpopexy is a reliable procedure that effectively and consistently resolves vaginal vault prolapse. Patients should be counseled about the low, but present risk, of reoperation for prolapse, stress incontinence, and complications. Prospective trials are needed to understand the effect of sacrocolpopexy on functional outcomes.
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              Long-term outcomes following abdominal sacrocolpopexy for pelvic organ prolapse.

              More than 225 000 surgeries are performed annually in the United States for pelvic organ prolapse (POP). Abdominal sacrocolpopexy is considered the most durable POP surgery, but little is known about safety and long-term effectiveness.
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                Author and article information

                Contributors
                Journal
                Int J Surg Case Rep
                Int J Surg Case Rep
                International Journal of Surgery Case Reports
                Elsevier
                2210-2612
                04 May 2016
                2016
                04 May 2016
                : 24
                : 219-222
                Affiliations
                [a ]Spine Surgery Department, St Franziskus Hospital, Köln, Schönsteinstr 63, 50825 Köln, Germany
                [b ]General Surgery Department, St Franziskus Hospital, Köln, Schönsteinstr 63, 50825 Köln, Germany
                Author notes
                [* ]Corresponding author. snunezpereira@ 123456gmail.com
                Article
                S2210-2612(16)30107-9
                10.1016/j.ijscr.2016.04.047
                4910140
                27289042
                ea830fe5-1651-4219-a8c9-c9cc7b429f6f
                © 2016 The Author(s)

                This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

                History
                : 14 February 2016
                : 27 April 2016
                : 27 April 2016
                Categories
                Case Report

                lumbosacral spondylodiscitis,rectal fistula,colpopexy,enterococcus spp.

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