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      A Bioprinted Liver-on-a-Chip for Drug Screening Applications.

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          Abstract

          The need for a liver-on-a-chip tissue model for drug screening is particularly important in tissue engineering because of the high frequency of drug-induced liver injury. Recently, a liver tissue model conducive to hepatotoxicity testing was developed by bioprinting hepatic spheroids encapsulated in a hydrogel scaffold into a microfluidic device.

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          Author and article information

          Journal
          Trends Biotechnol.
          Trends in biotechnology
          Elsevier BV
          1879-3096
          0167-7799
          Sep 2016
          : 34
          : 9
          Affiliations
          [1 ] Department of Biomedical Engineering, University of Connecticut, 260 Glenbrook Road, Storrs, CT 06269, USA.
          [2 ] Department of Biomedical Engineering, University of Connecticut, 260 Glenbrook Road, Storrs, CT 06269, USA; Department of Mechanical Engineering, University of Connecticut, 191 Auditorium Road, Storrs, CT 06269, USA. Electronic address: savas@engr.uconn.edu.
          Article
          S0167-7799(16)30060-9
          10.1016/j.tibtech.2016.05.014
          27291461

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