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      PiSZ alpha-1 antitrypsin deficiency (AATD): pulmonary phenotype and prognosis relative to PiZZ AATD and PiMM COPD.

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          Abstract

          The PiSZ genotype results in less severe deficiency of alpha-1 antitrypsin (AAT) than PiZZ. Less is known about phenotypic and prognostic features.

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          Author and article information

          Journal
          Journal ID (iso-abbrev): Thorax
          Title: Thorax
          Publisher: BMJ
          ISSN (Electronic): 1468-3296
          ISSN (Print): 0040-6376
          Publication date (Electronic): Oct 2015
          Volume: 70
          Issue: 10
          Affiliations
          [1 ] Centre for Translational Inflammation Research, University of Birmingham, Birmingham, UK.
          [2 ] Imperial College, London, UK.
          [3 ] Centre for Translational Inflammation Research, University of Birmingham, Birmingham, UK Heart of England NHS Foundation Trust, Birmingham, UK.
          Article
          Publisher Item ID: thoraxjnl-2015-206906
          DOI: 10.1136/thoraxjnl-2015-206906
          PubMed ID: 26141072

          Data availability:

          Keywords: COPD epidemiology, Alpha1 Antitrypsin Deficiency, Tobacco and the lung, Emphysema

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