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      PiSZ alpha-1 antitrypsin deficiency (AATD): pulmonary phenotype and prognosis relative to PiZZ AATD and PiMM COPD.

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          Abstract

          The PiSZ genotype results in less severe deficiency of alpha-1 antitrypsin (AAT) than PiZZ. Less is known about phenotypic and prognostic features.

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          Author and article information

          Journal
          Thorax
          Thorax
          BMJ
          1468-3296
          0040-6376
          Oct 2015
          : 70
          : 10
          Affiliations
          [1 ] Centre for Translational Inflammation Research, University of Birmingham, Birmingham, UK.
          [2 ] Imperial College, London, UK.
          [3 ] Centre for Translational Inflammation Research, University of Birmingham, Birmingham, UK Heart of England NHS Foundation Trust, Birmingham, UK.
          Article
          thoraxjnl-2015-206906
          10.1136/thoraxjnl-2015-206906
          26141072
          eac51919-b6ad-4e58-bf6e-c8ca60780688
          History

          COPD epidemiology,Alpha1 Antitrypsin Deficiency,Tobacco and the lung,Emphysema

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