Increasing incidence of immune-mediated necrotizing myopathy: single-centre experience.

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Immune-mediated necrotizing myopathy (IMNM) is characterized by the predominant presence of necrotic muscle fibres in muscle biopsy and variable response to immunosuppressive treatment. The aims of this study were to analyse the temporal trend of IMNM incidence in our centre over the past 10 years and to explore the role of statins as possible causative agents.

Related collections

Author and article information

Journal

Journal ID (iso-abbrev): Rheumatology (Oxford)

Title: Rheumatology (Oxford, England)

Publisher: Oxford University Press (OUP)

ISSN (Electronic): 1462-0332

ISSN (Print): 1462-0324

Publication date (Electronic): Nov 2015

Volume: 54

Issue: 11

Affiliations

[1 ] Clinical Department, Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Charles University in Prague.

[2 ] Department of Pathology and Molecular Medicine, 2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol, Prague, Czech Republic.

[3 ] Department of Pharmacy and Pharmacology, University of Bath and.

[4 ] Department of Pharmacy and Pharmacology, University of Bath and Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, UK.

[5 ] Clinical Department, Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Charles University in Prague, vencovsky@revma.cz.

Article

Publisher Item ID: kev229

DOI: 10.1093/rheumatology/kev229

PubMed ID: 26109604

SO-VID: eafa9d7f-ef4d-45ec-af1b-f4737684be03

History

Keywords: anti-3-hydroxy-3-methylglutaryl coenzyme A reductase autoantibodies,muscle biopsy,myositis,necrotizing myopathy

Data availability:

Keywords: anti-3-hydroxy-3-methylglutaryl coenzyme A reductase autoantibodies, muscle biopsy, myositis, necrotizing myopathy

Increasing incidence of immune-mediated necrotizing myopathy: single-centre experience.

Read this article at

Abstract

Related collections

HLA-G and immune tolerance in pregnancy

Author and article information

Journal

Affiliations

Article

History

Comments

Comment on this article

Similar content 51

Cited by 23