2
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      A novel gene, optrA, that confers transferable resistance to oxazolidinones and phenicols and its presence in Enterococcus faecalis and Enterococcus faecium of human and animal origin.

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          The oxazolidinone-resistant Enterococcus faecalis E349 from a human patient tested negative for the cfr gene and 23S rRNA mutations. Here we report the identification of a novel oxazolidinone resistance gene, optrA, and a first investigation of the extent to which this gene was present in E. faecalis and Enterococcus faecium from humans and food-producing animals.

          Related collections

          Author and article information

          Journal
          J. Antimicrob. Chemother.
          The Journal of antimicrobial chemotherapy
          1460-2091
          0305-7453
          Aug 2015
          : 70
          : 8
          Affiliations
          [1 ] Department of Veterinary Pharmacology, College of Veterinary Medicine, China Agricultural University, Beijing, China.
          [2 ] Institute of Clinical Pharmacology, Peking University First Hospital, Beijing, China.
          [3 ] The Second Affiliated Hospital of Zhejiang University, Zhejiang University, Hangzhou, China.
          [4 ] Institute of Farm Animal Genetics, Friedrich-Loeffler-Institut (FLI), Neustadt-Mariensee, Germany.
          [5 ] Tianjin Medical University General Hospital, Tianjin, China.
          [6 ] Institute of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, China.
          [7 ] Beijing Key Laboratory of Detection Technology for Animal Food Safety, China Agricultural University, Beijing, China.
          [8 ] Department of Veterinary Pharmacology, College of Veterinary Medicine, China Agricultural University, Beijing, China sjz@cau.edu.cn.
          Article
          dkv116
          10.1093/jac/dkv116
          25977397
          © The Author 2015. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

          Comments

          Comment on this article

          Similar content 479

          Cited by 112