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      Roles of Chlorogenic Acid on Regulating Glucose and Lipids Metabolism: A Review

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          Abstract

          Intracellular glucose and lipid metabolic homeostasis is vital for maintaining basic life activities of a cell or an organism. Glucose and lipid metabolic disorders are closely related with the occurrence and progression of diabetes, obesity, hepatic steatosis, cardiovascular disease, and cancer. Chlorogenic acid (CGA), one of the most abundant polyphenol compounds in the human diet, is a group of phenolic secondary metabolites produced by certain plant species and is an important component of coffee. Accumulating evidence has demonstrated that CGA exerts many biological properties, including antibacterial, antioxidant, and anticarcinogenic activities. Recently, the roles and applications of CGA, particularly in relation to glucose and lipid metabolism, have been highlighted. This review addresses current studies investigating the roles of CGA in glucose and lipid metabolism.

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          Thiazolidinediones

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            Chlorogenic acids and other cinnamates - nature, occurrence and dietary burden

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              Chlorogenic acids and other cinnamates - nature, occurrence, dietary burden, absorption and metabolism

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                Author and article information

                Journal
                Evid Based Complement Alternat Med
                Evid Based Complement Alternat Med
                ECAM
                Evidence-based Complementary and Alternative Medicine : eCAM
                Hindawi Publishing Corporation
                1741-427X
                1741-4288
                2013
                25 August 2013
                25 August 2013
                : 2013
                : 801457
                Affiliations
                1Institute of Liver Diseases, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, 528 Zhangheng Road, Pudong, Shang hai 201203, China
                2Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Pudong, Shanghai 201203, China
                3E-Institute of Traditional Chinese Internal Medicine of Shanghai Municipal Education Commission, 1200 Cailun Road, Pudong, Shanghai 201203, China
                Author notes

                Academic Editor: Yong-Qing Yang

                Article
                10.1155/2013/801457
                3766985
                24062792
                eb8c530a-32f9-481e-a074-d9bc4d844346
                Copyright © 2013 Shengxi Meng et al.

                This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 24 May 2013
                : 9 July 2013
                : 12 July 2013
                Funding
                Funded by: http://dx.doi.org/10.13039/501100001809 National Natural Science Foundation of China
                Award ID: 81173404
                Categories
                Review Article

                Complementary & Alternative medicine
                Complementary & Alternative medicine

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