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      Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma.

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          Abstract

          A recombinant humanized anti-IgE mAb, omalizumab, forms complexes with free IgE, blocking its interaction with mast cells and basophils; as a consequence, it might be effective in the treatment of asthma.

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          Author and article information

          Journal
          J Allergy Clin Immunol
          The Journal of allergy and clinical immunology
          Elsevier BV
          0091-6749
          0091-6749
          Aug 2001
          : 108
          : 2
          Affiliations
          [1 ] Department of Medicine, University of Wisconsin Hospital & Clinics, University of Wisconsin, Madison, 53792, USA.
          Article
          S0091-6749(01)65945-1
          10.1067/mai.2001.117880
          11496232
          eba7bd89-4286-41c0-90d8-467b6427e5e5
          History

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